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The degree to which or rate at which a drug or other substance is absorbed or becomes available at the site of physiological activity after administration.

bi′o·a·vail′a·ble (-lə-bəl) adj.


(Medicine) the extent to which a drug or other substance is taken up by a specific tissue or organ after administration; the proportion of the dose of a drug that reaches the systemic circulation intact after administration by a route other than intravenous. Also called: systemic availability
ˌbioaˈvailable adj


(ˌbaɪ oʊ əˌveɪ ləˈbɪl ɪ ti)

the extent to which a substance can be used by the body.
bi`o•a•vail′a•ble, adj.
References in periodicals archive ?
While inorganic trace minerals are relatively cheap, they suffer from poor bioavailability, or the degree to which an ingested nutrient is absorbed in a form that can be utilized in metabolism by the animal, as compared with some organic trace minerals," commented Karen Wedekind, Senior Research Scientist, Comparative Nutrition at Novus.
Ashland's objective is to work with innovative manufacturers of consumer care products at the early stages of product development, and to deliver bioavailability solutions that lead to better market opportunities for customers.
Researchers at the University of Massachusetts plan to determine the relationship between the physicochemical characteristics of nano-laminated biopolymer coatings and the bioavailability of encapsulated lipids.
The current curcumin product from Theravalues, Theracurmin, proved 27 times higher bioavailability than ordinary curcumin powder.
In the laboratory, the researchers also tested the bioavailability of beta-carotene from orange-fleshed honeydew melon tissue.
The comparative bioavailability study follows a positivescientific advice meeting with the German Federal Institutefor Drugs and Medical Devices (BfArM) announced by RedHill in November 2013.
The typically low systemic bioavailability of the lipophilic curcumin is attributed to its poor solubility in the aqueous phase of the digestive tract and its rapid metabolism and excretion from the body.
A vitamin D bioavailability test was performed on all subjects.
Patients may be harmed if the bioavailability of drugs is either impaired, resulting in reduced efficacy, or enhanced, resulting in toxicity.
Drug bioavailability; estimation of solubility, permeability, absorption and bioavailability, 2d ed.
Physicians can help minimize the potential for abuse of opioid pain medications by considering the agents' delivery route, bioavailability, and pharmacokinetics, said Dr.
Bioavailability of even the newer rapid-release formulation of levothyroxine known as Levoxyl is reduced 40% by taking the tablets close to a meal.