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The degree to which or rate at which a drug or other substance is absorbed or becomes available at the site of physiological activity after administration.

bi′o·a·vail′a·ble (-lə-bəl) adj.


(Medicine) the extent to which a drug or other substance is taken up by a specific tissue or organ after administration; the proportion of the dose of a drug that reaches the systemic circulation intact after administration by a route other than intravenous. Also called: systemic availability
ˌbioaˈvailable adj


(ˌbaɪ oʊ əˌveɪ ləˈbɪl ɪ ti)

the extent to which a substance can be used by the body.
bi`o•a•vail′a•ble, adj.
References in periodicals archive ?
Objective: The objective of this proposal is the elucidation of general principles for the design of bioavailable peptide-derived macrocyclic compounds and their use for the development of inhibitors of proteinprotein (PPI) and proteinRNA interactions (PRI).
The acquisition is part of the company's plan to combine this enhanced bioavailable nutrient and the natural symbiotic immune system developed by Van Pham, an agricultural expert, for premium organic farming.
Our study found that low levels of both total vitamin D and bioavailable vitamin D appear to be associated with poor cardiovascular outcomes," Dr.
For doctors who treat these patients, the most important measures of vitamin D are known as total vitamin D and bioavailable vitamin D, since both were "the most accurate in predicting harmful cardiovascular events," said the findings.
The net effect is that the serum concentration of bioavailable 25(OH)D is very similar between whites and blacks (Powe CE et al.
Bioavailable plant extracts company Plandai Biotechnology Inc (OTCQB:PLPL) reported on Thursday the execution of an agreement to use the Diego Pellicer name for its Phytofare cannabis extracts in medical and pharmaceutical marijuana applications.
EPA Elite differs from the study product in that it is formulated in the more bioavailable triglyceride form, the company said.
In its Form 8-K filing with the US Securities and Exchange Commission (SEC), the borrower, which produces highly bioavailable plant extracts, said it had executed the final loan documents.
To facilitate public access to more natural, powerful, effective and bioavailable formulations of hydroxytyrosol, Creagri, Inc.
The beverage would also deliver higher concentrations of lutein in a more bioavailable matrix than do many common supplements.
Bioavailable sex steroids comprise the fractions that are free or bound to albumin in the circulation, and in contrast to the fraction bound to SHBG, it is these fractions that have rapid access to target tissues (26,27).