bioequivalent


Also found in: Medical.

bi·o·e·quiv·a·lent

 (bī′ō-ĭ-kwĭv′ə-lənt)
adj.
Acting on the body with the same strength and similar bioavailability as the same dosage of a sample of a given substance. Used of differing formulations of a drug or chemical compound.

bi′o·e·quiv′a·lence n.
Translations

bioequivalent

adj bioequivalente
References in periodicals archive ?
Riyadh, Jumada II 11, 1439, February 27, 2018, SPA -- Saudi Food and Drug Authority (SFDA) has announced a cancellation of registrations of four products because two of them are not bioequivalent to the reference product, and the other two products have not been marketed for more than two years.
Is there a scientific rationale for making drug products with 'comparable' bioavailability, although not being proven bioequivalent products, interchangeable with each other?
Greenstone recently rolled out amoxicillin 875-mg tablets, USP, AB-rated and bioequivalent to Amoxil; cefadroxi1 500-mg capsules, USP, AB-rated and bioequivalent to Duricef; cefdinir 300-mg capsules, AB-rated and bioequivalent to Omnicef; and cefprozil 250- and 500-mg tablets, USP, AB-rated and bioequivalent to Cefzil.
Results of the study indicate that the MetControl Metformin chewing gum and traditional Metformin tablets are bioequivalent in respect of both the rate and the extent of systemic absorption such that MetControl and Metformin tablets are therapeutically equivalent and therefore interchangeable.
Under data exclusivity, a controversial rule first imposed in 1987, for a period of about eight years after approval of a new drug, a country cannot accept an application for a generic bioequivalent to a brand-name drug even if the patent is expired or is otherwise not a problem, because that is called "unfair" use of the knowledge that the brand-name drug worked in the first place.
812) would let the Food and Drug Administration approve generic drugs that are not bioequivalent to their brand-named counterparts.
Fluocinonide E Cream is bioequivalent to Medicis' Lidex(R), and the market for this product is estimated by industry sources to be approximately $5,000,000.
The FDA has determined that these formulations, which will be manufactured at Bentley's facilities in Spain, are bioequivalent and have the same therapeutic effect as that of the reference drug, Zocor([R]) (Merck & Co.
Recent approvals include paroxetine tablets, bioequivalent to GSK's Paxil; benzonatate (100- and 200-mg) capsules, bioequivalent to Forest Laboratories Inc.
Diflorasone Diacetate Cream is bioequivalent to Dermik Laboratories' Psorcon(R) Cream.
The breadth of his business experience will allow him to make a major contribution to the development and marketing of bioequivalent products utilizing the ACCU-BREAK[TM] technologies, as well as allowing him to play an important role in our technology out-licensing efforts.
Recently launched products include Zolpidem Tartrate tablets, AB-rated and bioequivalent to sanofi-aventis' Ambien; Azithromycin for injection; Cabergoline tablets, AB-rated and bioequivalent to Pfizer's Dostinex; and Moexipril Hydrochlorothiazide tablets, AB-rated and bioequivalent to Schwarz Pharma's Uniretic.