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biogenic amine |
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| These correlations, which indicate an increased dopamine metabolism, agree with recent experimental data in rats, showing that cadmium interferes with biogenic amine release from the hypothalamus, thereby inhibiting prolactin secretion (Lafuente et al. Cerebrospinal fluid biogenic amine metabolites in fibromyalgia/fibrositis syndrome and rheumatoid arthritis. Indeed, Rosin and Martin (1981) reported significant reductions in uptake of biogenic amine neurotransmitters into synaptosomes after exposure to Aroclor mixtures, whereas Mariussen and Fonnum (2001) recently reported that only noncoplanar PCB congeners inhibited uptake of labeled DA into striatal synaptosomes. |
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