Coverage includes laboratory biosafety in containment laboratories, hazard criteria and categorization of microbes classification systems, technical and practical aspects of BSL-3 laboratories, animal biosafety level
3 facility--enhancements when dealing with large animals, personal protective equipment, shipping of infectious substances according to IATA-DGR regulations, disinfection and decontamination, fumigation of spaces, bridging the gap between requirements of biocontainment and diagnostics, risk assessment procedures, and biosecurity.
The facility and equipment are designed to isolate the virus from manufacturing associates, therefore reducing the biosafety level
The biosafety level
2 (BSL-2) Processing Innovation Laboratory functions as a center for the development of new processing and process con-trol technologies.
All residual biological samples collected during the patient's hospital stay were sent to the virology laboratory of the Spallanzani Hospital (Italy's national reference laboratory for viral hemorrhagic fever viruses, BioSafety Level
4) in compliance with biosafety procedures.
Unknown bacteria isolated from food were not studied further, as that would constitute a Biosafety Level
The lab, at 3 Discovery Drive, is a $31 million, 41,000-square-foot Biosafety Level
2 and 3 facility that eventually
While Duke researchers and others have worked with these agents, animal research testing requires carefully planned and constructed biosafety level
3 labs with specialized equipment, notes Richard Frothingham, MD, building director of a new facility that's up to the task.
Baxter's vaccine production facilities are engineered for BioSafety Level
3 production, which means that they can use wild-type strains to help accelerate production.
Working under biosafety level
3, the second-highest level of protection against biohazards, Tumpey's team found that the reconstructed virus killed otherwise-healthy mite in 3 to 5 days.
The first problem it encountered was that the animal biosafety level
three (ABSL-3) facility where the experiments were to take place hasn't been built.
Highly pathogenic strains should not be cultured routinely and require Biosafety Level
3+ (BSL) or higher facilities for culture.
Although the WHO (1) and the CDC (2) recommend that blood samples from patients in whom SARS is suspected should be analyzed under biosafety level
II conditions, most high-throughput analyzers in the clinical chemistry laboratory use open tubes and therefore do not meet the biosafety level