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blood-brain barrier

   Also found in: Medical, Legal, Financial, Encyclopedia, Wikipedia 0.01 sec.
blood-brain barrier (bldbrn)
n.
A physiological mechanism that alters the permeability of brain capillaries, so that some substances, such as certain drugs, are prevented from entering brain tissue, while other substances are allowed to enter freely.

blood-brain barrier
A physiological mechanism that alters the permeability of capillaries in the brain, so that some substances, such as certain drugs, are prevented from entering brain tissue, while other substances are allowed to enter freely.
ThesaurusLegend:  Synonyms Related Words Antonyms
Noun1.blood-brain barrier - a mechanism that creates a barrier between brain tissues and circulating blood; serves to protect the central nervous system; "the brain was protected from the large molecules of the virus by the blood-brain barrier"
barrier - anything serving to maintain separation by obstructing vision or access


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Reported online in the March 3, 2009, issue of the Journal of Neurotrauma, the S-100B test can relay critical information about how the blood-brain barrier is functioning after a head injury.
The research team examined the functions of a protein known as NanA in order to discover how an entire bacterium can breech the blood-brain barrier and gain access to the central nervous system.
The invention further provides conjugates of the foregoing compounds which can cross the blood-brain barrier and pharmaceutical compositions containing such conjugates.
 
 
 
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