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botulinum toxin

   Also found in: Medical, Acronyms, Encyclopedia, Wikipedia 0.03 sec.
botulinum toxin  (bch-lnm)
Any of several enzymes produced by the bacterium Clostridium botulinum that are extremely potent neurotoxins. Botulinum toxin interferes with the ability of neurons to release acetylcholine at nerve-muscle junctures, thereby inducing the paralysis of botulism. Botulinum toxin is resistant to enzymatic digestion in the body and is used as an antispasmodic and a treatment for wrinkles by paralyzing facial muscles. Also called botulin.
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Noun1.botulinum toxin - any of several neurotoxins that are produced by the anaerobic bacterium Clostridium botulinum; causes muscle paralysis
Botox, botulinum toxin A - a neurotoxin (trade name Botox) that is used clinically in small quantities to treat strabismus and facial spasms and other neurological disorders characterized by abnormal muscle contractions; is also used by cosmetic surgeons to smooth frown lines temporarily
neurolysin, neurotoxin - any toxin that affects neural tissues
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Kirazli and colleagues (57) compared 3 mL of 5% phenol injections with 400 units of botulinum toxin (BTX) type A injections for the management of the spastic foot in 20 subjects.
Pharmacologic management of spasticity following stroke by Gallichio, Joann E. / Physical Therapy
Botulinum toxin has been developed as a biologic weapon by various countries and terrorist groups and could be disseminated by deliberate contamination of foods or aerosolization (10).
Foodborne botulism in the United States, 1990-2000 by Maslanka, Susan / Emerging Infectious Diseases
On July 20, the Food and Drug Administration approved injections of botulinum toxin type A, which Allergan markets as Botox, for treating hyperhidrosis that doesn't improve with other nonsurgical treatments, such as antiperspirant ointments.
Severe sweating treated with Botox by Science News
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