osteogenesis imperfecta(redirected from brittle-bone disease)
Also found in: Thesaurus, Medical, Encyclopedia.
A genetic disease marked by abnormal fragility and plasticity of bone, with recurring fractures resulting from minimal trauma.
[New Latin : osteogenesis + Latin imperfecta, feminine of imperfectus, incomplete.]
(Pathology) a hereditary disease caused by a collagen abnormality, causing fragility of the skeleton which results in fractures and deformities. Also called: brittle bone syndrome