The increased plasma concentrations of dextromethorphan after dosing with AXS-09, which contains the chirally pure S-enantiomer of bupropion
, are comparable to those achieved with dosing of the company's first generation product candidate AXS-05 which contains racemic bupropion
M2 EQUITYBITES-July 6, 2017-Jubilant Life Sciences receives final approval from US FDA for Bupropion
M2 PHARMA-February 1, 2017-Sun Pharma recalls anti-depressant drug Bupropion
Neuropsychiatric adverse events do not increase significantly in smokers treated with either varenicline or bupropion
, a large cohort study shows.
Patients with major depressive disorder (MDD) who have previously failed one or two antidepressant treatments will be treated in an open-label fashion with bupropion
during a 6-week lead-in period.
Smokers have a higher probability of quitting smoking and a better overall cessation experience when taking varenicline compared to bupropion
and to placebo--unmedicated assisted smoking cessation--according to a study published in the journal JAMA Psychiatry.
A / Yes, nortriptyline approximately doubles smoking cessation rates, an effect comparable to bupropion
Researchers found that the use of a nicotine patch and the combination of nicotine-replacement medications bupropion
and varenicline helped a greater percentage of smokers quit than a nicotine patch and bupropion
The three smoking cessation agents bupropion
, varenicline, and nicotine replacement therapy did not raise the risk of serious adverse cardiovascular events in a network meta-analysis of 63 randomized clinical trials.
The three therapies in the study included nicotine replacement gum and patches, nicotine addiction treatment varenicline (Chantix), and the antidepressant bupropion
Some recent studies suggested that bupropion
works as a dopamine-uptake inhibitor, which might explain mild abuse potential of this drug.
Human laboratory data published in 2010 suggested that bupropion
, a dopaminergic and norepinephrine reuptake inhibitor, may be helpful for decreasing Internet video game addiction (Exp.