After that, bursa of Fabricius
, thymus, and spleen were collected and weighed to obtain the relative organ weights using the following formula: Relative weight of immune organ (g/kg) = immune organ weight (g) / body weight (kg).
In the heart (5/5), brain (2/2), esophagus (2/2), pancreas (2/2), proventriculus (2/ 2), gizzard (1/1), bursa of Fabricius
(1/1), oviduct (1/1), and skeletal muscle (1/1) staining was observed only in the lumen of blood vessels.
The virus was also detected in the bursa of fabricius
on days 2 and 6 PI and in thymus and liver on day 2 PI.
The thymus, spleen and bursa of Fabricius
are the main immune organs of the chicken.
Scoring microscopic lesions in the bursa of fabricius
thymus spleen and kidney in gnotobiotic and battery reared White Leghorns experimentally infected with infectious bursal disease virus.
21-26) On histologic examination, lymphocyte depletion and the presence of characteristic intracytoplasmic botryoid inclusion bodies within lymphoid tissues, commonly in macrophages and particularly in the bursa of Fabricius
, have frequently been reported either singly or together in infected birds.
The target organ of infectious bursal disease virus (IBDV) is the bursa of Fabricius
which is specific reservoir for B lymphocytes.
The 3-d averages of the body weight, and the weights of the bursa of Fabricius
and gizzard in the Xase6 group were higher than those in the control group (p < 0.
It has been reported that delayed access to feed impairs not only intestinal development but also development of gut-associated lymphoid tissue (GALT) like the bursa of fabricius
, cecal tonsils and meckel's diverticulum.
Testing of samples from pigeons with "young pigeon sickness" showed that the viral loads were high in the bursa of Fabricius
(up to 2.
The breast muscle (pectoralis major), bursa of Fabricius
, liver, spleen, and abdominal fat were then removed by trained personnel and weighed.
Replication of PiCV could be proved on the basis of histologic findings of multiglobular inclusion bodies, mainly observed in macrophages of the bursa of Fabricius