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busulfan

   Also found in: Medical, Encyclopedia, Wikipedia 0.01 sec.
bu·sul·fan  (by-slfn)
n.
An alkylating agent, C6H14O6S2, that is used as an antineoplastic drug in the treatment of chronic myelocytic leukemia.

[bu(tane) + alteration of sulfon(ate).]


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Medication associated with mastalgia Common Oral contraceptives Hormone replacement therapy Antidepressants Digoxin Methyldopa Spironolactone Chlorpromazine Other Amphetamines Anabolic steroids Busulfan (and other chemotherapeutic agents) Cimetidine Clomiphene Corticosteroids Insulin Isoniazid (and other antituberculosis drugs) Ketoconazole Marijuana Reserpine Spironolactone Testosterone Tricyclic antidepressants Table II.
Other topics include the synergistic anti-tumor activity of metronomic dosing chemotherapy in combination with liposomal anti- cancer drugs, the design of novel anti-cancer drugs utilizing busulfan for optimizing pharmacological properties and pattern recognition techniques for elucidating clinical efficacy, and insights into the mode of action of bioreductive ruthenium cytotoxins.
Chemotherapy and Targeted Agents That May increase Risk of Cardiotoxicity Chemotherapy * Anthracyclines * 5-fluorouracil/capecitbine * Cyclophosphamide/ifosphamide * Paclitaxel/docetaxel * Cisplatin * Mitomycin C * Busulfan * Bleomycin * Mitoxantrone * Etoposide * Vinca alkaloids Targeted Therapies * Trastuzumab * Lapatinib * Sunitinib * Sorafenib * Rituximab * Imatinib mesylate * Bevacizumab * Interferons/interleukins * Arsenic trioxide Note.
 
 
 
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