busulfan


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bu·sul·fan

 (byo͞o-sŭl′fən)
n.
An alkylating agent, C6H14O6S2, that is used as an antineoplastic drug in the treatment of chronic myelogenous leukemia.

[bu(tane) + alteration of sulfon(ate).]

busulfan

(bjuːˈsʌlfæn)
n
a drug used to treat cancer
Translations

busulfan

n busulfán m, busulfano (INN)
References in periodicals archive ?
Besides the Revela and Kenalog-40 generics, other recent launches from Amneal include busulfan injection 60 mg/10 ml (6 mg/1 ml), a generic version of Busulfex; progesterone capsules in 100 mg and 200 mg strengths, a generic of Prometrium; bumetanide tablets in 0.
Results presented include interim results from a Phase I/II clinical gene therapy study for newly diagnosed infants withX-SCID using a safety-modified lentiviral vector and targeted reduced exposure to busulfan.
Unlike the prior studies, the level of busulfan in the patients blood is pharmacologically targeted to avoid variability in blood levels and improve safety.
Pursuant to its partnership with Aspen, Mylan will commercialise Busulfan Injection in60 mg/10 ml(6 mg/ml) single-dose vial in the US.
Ionizing radiation and busulfan inhibit murine bone marrow cell hematopoietic function via apoptosis-dependent and -independent mechanisms.
Chronic graft versus host disease (GVHD), skin chronic GVHD, a HSCT regimen that included busulfan conditioning, and a family history of early male-pattern alopecia were all significantly associated with postHSCT permanent alopecia (P less than .
Among these, the high-risk group is associated with an overall 80% chance of premature ovarian failure (POF) which mostly comprises alkylating agents such as cyclophosphamide (CYP), busulfan and chlorambucil.
Quantification of busulfan in saliva and plasma in haematopoietic stem cell transplantation in children: validation of liquid chromatography tandem mass spectrometry method.
The drugs commonly causing pigmentation are cyclophosphamide, hydroxyurea, doxorubicin, cisplatin, fluorouracil, etoposide, busulfan, and bleomycin.
The price of leukaemia treatment busulfan rose from PS5.
In June 2013, the patient received human leukocyte antigen (HLA)-identical sibling HSCT with a conditioning regimen of busulfan and cyclophosphamide.
Similarly, overexpression of GDNF and its mRNA has been reported following busulfan treatment, the drug which eliminates germ cells from seminiferous tubules in mice (19-21).