There is no cross-reactivity with procalcitonin and calcitonin
from other species (pig, salmon, chicken) at concentrations <40 mg/L.
The patient's serum calcitonin
level was elevated, however, and a second fine-needle aspiration biopsy sample showed immunoreactivity for calcitonin
, a polypeptide, is thought to augment bone formation by increasing osteoblast activity, he said.
is a very safe drug that has been widely used for many years and is currently being assayed for the treatment of osteoarthritis and various musculoskeletal clinical painful conditions.
In a Phase III global, randomized, double-blind clinical study in postmenopausal women with osteoporosis known as the ORACAL trial, Tarsa's once-daily oral calcitonin
demonstrated superiority to both placebo and commercially-available nasal calcitonin
spray in increasing bone mineral density at the lumbar spine after 48 weeks.
The second two-year, Phase III Study 2302, which also assesses safety and efficacy of oral calcitonin
in patients with osteoarthritis of the knee, is currently ongoing.
Food and Drug Administration (FDA) for Ostora, its oral calcitonin
tablet for the treatment of postmenopausal osteoporosis.
today announced that it presented a new meta-analysis showing that salmon calcitonin
does not appear to be associated with an increased risk of cancer in postmenopausal women.
Although expenses have been reduced due to the elimination of our expenditures for the oral calcitonin
program, as well as reductions from our recent restructuring, we will need additional sources of cash in order to maintain our future operations.
PINK: UGNE), a leader in the design, delivery, manufacture and development of peptide-based therapeutics, today announced that the Food & Drug Administration (FDA) has posted notice of an Advisory Committee Meeting scheduled on March 5, 2013 to discuss whether the benefit of calcitonin
salmon for the treatment of postmenopausal osteoporosis outweighs a potential risk of cancer.
Oral salmon calcitonin
, which uses the proprietary absorption enhancing Eligen([R]) Drug Delivery Technology, is being studied in osteoarthritis and osteoporosis by Novartis Pharma AG and Nordic Bioscience.
Poster Presentation at ASBMR 2012 Concludes One-Year Use of Tarsa's Oral Calcitonin
Is Not Associated with Increased Risk of Cancer-