In the order Coleoptera, only Meloidae, Oedemeridae and Staphylinidae release vesicant chemicals that cause dermatitis and conjunctivitis (the first two release cantharidin
and the latter, pederin).
Silverberg NB, Sidbury R, Mancini AJ: Childhood molluscum contagiosum:Experience with cantharidin
therapy in 300 patients.
is found in blister beetles, which feed on alfalfa and other crops that are in horse food.
The discovery that cantharidin
inhibits PP5, has led to further research of Protein Phosphatase 5 inhibitors.
4] Bulgakov VP, Tchernoded GK, Mischenko NP, Khodakovskaya MV, Glazunov VP, Radchenko SV, Zvereva EV, Fedoreyev SA & Zhuravlev YN (2002) Effect of salicylic acid, methyl jasmonate, ethephon and cantharidin
on anthraquinone production by Rubia cordifolia callus cultures transformed with the rolB and rolC genes.
Another study in pediatric patients showed that combination therapy with cantharidin
and nightly application of imiquimod for 5 weeks resulted in greater than 90% clearing in 12 of 16 (75%) patients.
Systematic retention of ingested cantharidin
Stwff o'r enw cantharidin
sy'n yr olew, a hwn sy'n codi'r pothelli, ac mae'n medru achosi chwydd ar y croen hefyd.
Attending physicians noted that the symptoms resembled those seen in men who had overindulged in a drug called cantharidin
-- popularly known as Spanish fly -- which is extracted from a particular beetle for its purported value as an aphrodisiac.
Lyssa vesicatoria is what was popularly known as 'the Spanish fly', a little bug which exudes a substance called cantharidin
In contrast, NR-mediated NO synthesis in spinach was shown to be inhibited by cantharidin
(Rockel et al.