capreomycin


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cap·re·o·my·cin

 (kăp′rē-ō-mī′sĭn)
n.
An antibiotic that is derived from a bacterium (Streptomyces capreolus) and is used in its sulfate form to treat tuberculosis.

[Latin capreolus, diminutive of caper, capr-, goat + -mycin.]
References in periodicals archive ?
dagger]) Resistance among the following drugs were considered: isoniazid, rifampin, ethambutol, pyrazinamide, kanamycin, any fluoroquinolone, amikacin, and capreomycin.
If you have drug-resistant TB, a combination of antibiotics called fluoroquinolones and injectable medications, such as amikacin, kanamycin or capreomycin, are generally used for 20 to 30 months.
5 To control these MDR-TB strains, second-line drugs which include capreomycin, kanamycin or amikacin are used; however, these drugs have more toxic effect and are more expensive.
Rapid diagnosis of drug resistance to fluoroquinolones, amikacin, capreomycin, kanamycin and ethambutol using genotype MTBDRsl assay: A meta-analysis.
14] could be due use to different aminoglycosides such as kanamycin, capreomycin, amikacin, and streptomycin were used for longer duration (up to 12 months), which could have resulted in increased number of ototoxicity (41.
The association between TB and HIV, and the increasing emergence of MDR-TB and extensively drug-resistant TB (XDR-TB; such strains are resistant to second-line drugs, for example capreomycin, kanamycin, and/or amikacin), have worsened the situation; the threat to health is serious (Matteelli et al.
Patients with second-line drug resistance, toxicity, or contraindications to the standardised regimen can access individualised regimens including capreomycin, para-aminosalicylic acid, clofazimine, linezolid and bedaquiline.
For TB, they include capreomycin, kanamycin, amikacin, ethionamide, para-aminosalicylic acid, cycloserine, ciprofloxacin, ofloxacin, levofloxacin, clofazimine, and the new medicines bedaquiline and delamanid.
tuberculosis that is resistant to not only INH and RIF, but also to other medication classes that comprise the backbone of drug-resistant TB therapy, namely a quinolone and one of the second-line inject able drugs (kanamycin [KAN], amikacin [AMK], or capreomycin [CAP]) [2].
Identification of the biosynthetic gene cluster and an additional gene for resistance to the antituberculosis drug capreomycin.
Given the high background rates of TB and MDR-TB in several countries, regimens are often constructed around a backbone of capreomycin and para-aminosalicylic acid
XDR-TB: Extensively-drug Resistant TB (XDR-TB) is defined as TB caused by mycobacterium tuberculosis resistant to isoniazid, rifampicin, quinolones and any 1 of 3 injectables: kanamycin, capreomycin or amikacin.