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A pungent alkaloid, C18H27NO3, derived from certain capsicums that is a strong irritant to skin and mucous membranes and is used in some topical pain relievers and in pepper sprays.

[Alteration (perhaps influenced by Latin capsa, box) of earlier capsicin : capsic(um) + -in.]


(Biochemistry) a colourless crystalline bitter alkaloid found in capsicums and used as a flavouring in vinegar and pickles. Formula: C18H27O3N
[C19 capsicine, from capsicum + -ine2; modern form refashioned from Latin capsa box, case + -in]


(kæpˈseɪ ə sɪn)

a colorless, crystalline, bitter compound, C18H27NO3, present in capsicum.
[1885–90; earlier capsicine= capsic (um) + -ine2]
ThesaurusAntonymsRelated WordsSynonymsLegend:
Noun1.capsaicin - colorless pungent crystalline compound derived from capsicum; source of the hotness of hot peppers of the genus Capsicum such as chili and cayenne and jalapeno
capsicum, capsicum pepper plant, pepper - any of various tropical plants of the genus Capsicum bearing peppers
chemical irritant - a substance producing irritation


n capsaicina
References in periodicals archive ?
Researchers have discovered that capsaicin directly stimulates pain-sensitive neurons in the mouth and skin via specific protein receptors (the same protein sensors that heat stimulates, which is why chili peppers taste hot).
CNTX-4975 is based on Centrexion's proprietary STRATI technology (Synthetic TRans cApsaicin ulTra-pureInjection), a highly potent, ultrapure, synthetic form of trans-capsaicin (a medicine traditionally derived from the chili plant).
As this review of the medical literature will reveal, there is evidence to support the use of capsaicin to relieve osteoarthritis (OA) and postherpetic neuralgia (PHN) and support for green tea to serve as a lipid-lowering agent and help treat diabetes.
The discomfort of eating high amounts of capsaicin is meant to deter overconsumption, but for those able to overcome both the physical and mental pain, the consequences can range from unpleasant to just plain deadly.
Capsaicin is available on prescription in the form of gels, creams and plasters.
Therefore, our contribution presents data on possible effective treatments to mitigate acute effects: the use of haloperidol and capsaicin.
Capsaicin is also used to treat arthritis and is regarded as an effective painkiller for muscle and backache.
The high-dose capsaicin containing dermal patch Qutenza (Rx) was developed by NeurogesX and licensed to Astellas Pharma Europe in 2009.
For instance, it explains hot versus sweet paprika; the difference lies with the amount of capsaicin each contains.
Actually there is not much difference apart from the capsaicin content.
Capsaicin from the genus Capsicum, is the active component of hot chili peppers.
The company's proprietary pipeline consists of injectable analgesic capsaicin, known as trans-capsaicin, which is currently being evaluated in clinical trials for the treatment of pain associated with chronic conditions.