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An ACE inhibitor drug, C9H15NO3S, used in the treatment of hypertension, congestive heart failure, and other cardiovascular disorders.

[(mer)capt(an) + -pr- (pr(opane) or pr(oline)) + alteration of -yl.]


(Pharmacology) an ACE inhibitor used to treat high blood pressure and congestive heart failure


(ˈkæp tə prɪl)

a white, crystalline powder, C9H15NO3S, used as an antihypertensive.
ThesaurusAntonymsRelated WordsSynonymsLegend:
Noun1.captopril - a drug (trade name Capoten) that blocks the formation of angiotensin in the kidneys resulting in vasodilation; used in the treatment of hypertension and congestive heart failure
ACE inhibitor, angiotensin-converting enzyme inhibitor - an antihypertensive drug that blocks the formation of angiotensin II in the kidney, leading to relaxation of the arteries; promotes the excretion of salt and water by inhibiting the activity of the angiotensin converting enzyme; also used to treat congestive heart failure


n captopril m
References in periodicals archive ?
Antihypertensive medicines dispensed for free during SNP were: (i) beta-blocking agents: atenolol 25 mg and propranolol hydrochloride 40 mg; (ii) diuretics: hydrochlorothiazide 25 mg; and (iii) agents acting on the renin-angiotensin system inhibitors (Class C09 on European Pharmaceutical Marketing Research Association (EphMRA) Anatomical Classification) including (a) the angiotensin-converting-enzyme (ACE) inhibitors captopril 25 mg and enalapril maleate 10 mg; and (b) the angiotensin II antagonist or angiotensin receptor blocker (ARB) losartan potassium 50 mg (10).
Captopril (98% purity) was purchased from Sigma-Aldrich (St.
TEHRAN (FNA)- Captopril is an edible drug that plays an essential role in the treatment of heart attack, heart malfunction and high blood pressure and persistent consumption of this drug results in side effects.
Moreover, captopril for hypertension was given to two IAS patients.
Literature review shows multiple reports of DILI with captopril (2, 3), ramipril (4), fosinopril (5, 6) and enalapril.
His condition stabilised within 1 week; he was discharged and prescribed captopril and frusemide, and advised to follow-up regularly.
The EMA's Paediatric Committee (PDCO) supported the paediatric investigation plan (PIP) for the development of captopril, a drug designed to treat heart failure in children.
In a randomized controlled trial, Toprak administered captopril to 48 patients and placebo to 32 patients with a baseline creatinine of less than 2 mg/dL.
We have evidence from the laboratory that a substance in egg white - it's a peptide, one of the building blocks of proteins - reduces blood pressure about as much as a low dose of Captopril, a high-blood-pressure drug," Yu stated.
The first group involved 130 hypertensive type 2 diabetic patients taking enalapril, captopril (Converting Enzyme inhibitors), valsartan or telmisartan (Angiotensin II receptor blockers) as monotherapy whereas group 2 involved 92 type 2 diabetic patients with normal blood pressure.
14) se describen tres casos de prematuros con falla cardiaca con dosis inicial de captopril recomendada para el nacido a termino de 0,01 mg/kg/dosis cada 8 a 12 horas y para el nacido pretermino de 0,05-0,1 mg/kg/dosis cada 8 a 24 horas, donde la dosis en neonatos a termino es 10 veces mayor, sin cambio en la dosis de enalapril para los neonatos a termino o pretermino.