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An ACE inhibitor drug used in the treatment of hypertension, congestive heart failure, and other cardiovascular disorders.

[(mer)capt(an) + -pr- (pr(opane) or pr(oline)) + alteration of -yl.]


(Pharmacology) an ACE inhibitor used to treat high blood pressure and congestive heart failure


(ˈkæp tə prɪl)

a white, crystalline powder, C9H15NO3S, used as an antihypertensive.
ThesaurusAntonymsRelated WordsSynonymsLegend:
Noun1.captopril - a drug (trade name Capoten) that blocks the formation of angiotensin in the kidneys resulting in vasodilation; used in the treatment of hypertension and congestive heart failure
ACE inhibitor, angiotensin-converting enzyme inhibitor - an antihypertensive drug that blocks the formation of angiotensin II in the kidney, leading to relaxation of the arteries; promotes the excretion of salt and water by inhibiting the activity of the angiotensin converting enzyme; also used to treat congestive heart failure


n captopril m
References in periodicals archive ?
Effect of angiotensin-converting-enzyme inhibition compared with conventional therapy on cardiovascular morbidity and mortality in hypertension: the Captopril Prevention Project (CAPPP) randomised trial.
So far, the FDA has approved only a few venom-based drugs, such as captopril (KAP-tuh-pril).
Thus, Captopril and Mevacor, two successful drugs to treat hypertension and high cholesterol respectively, propelled Squibb and Merck into successful world class pharmaceutical companies.
The benefits of captopril extend beyond its ability to lower blood pressure; it may directly protect the kidney's glomeruli.
Milanese says five generic companies have made substantial preparations to market captopril, the generic version of this drug, in August.
A study reported in The New England Journal of Medicine last November showed that the heart medication captopril (Capoten) reduced by 50 percent the risk of death or ESRD.
Chicago, and his colleagues report that captopril -- a type of angiotensin-convertlag-enzyme (ACE) inhibitor- "protects renal function in insulin-dependent diabetic nephropathy and is significantly more effective than blood-pressure control alone.
FibroGen presented data from multiple studies designed to examine the effects of FG-3019 alone and in combination with current therapeutics, captopril (ACEi) and losartan (ARB), on diabetic vascular and cardiac complications including arterial passive stiffness, cardiac dysfunction, and vascular permeability.
Methods: SHRs were divided into four groups: SHR control, SHR + 40 mg/kg captopril, SHR + 30 mg/kg OMT and SHR + 60 mg/kg OMT.
In a randomized, double-blind, active-controlled trial, scientists compared the efficacy of olive leaf against captopril (Capoten[R]), an antihypertensive drug.
Nirthanan said many common drugs such as the widely prescribed blood pressure medication Captopril and anti-clotting drug Eptifibatide have been developed from snake and other animal venoms.