Three possible reasons for inhibitory effect of de novo fatty acid synthesis by stearate are as follows: i) Stearate inhibited de novo synthesis of fatty acid by down-regulating the mRNA expression of ACACA and FASN; ii) Long-chain acyl-CoA competed with newly synthesized medium-chain acyl-CoA for the sn-2 and sn-3 positions of the triacylglycerol backbone; iii) long-chain acyl-CoA inhibited de novo synthesis of fatty acid by suppression of acetyl-CoA carboxylase
(Hansen and Knudsen.
Down-regulation of mRNA levels of the lipogenic enzymes, fatty acid synthase (FAS), acetyl-coA carboxylase
(ACC) and stearoyl-coenzyme A desaturase-1 (SCD1) in the liver and perirenal white adipose tissue in C57BL/6J mice was also seen (Murase et al.
2] concentrations in the light and the dark on diurnal malate rhythm and phosphoenolpyruvate carboxylase
activities in leaves of Littorella uniflora (L.
These changes may be the result of reduced hepatic glucose production because we found that the pyruvate carboxylase
(Pcx), the first of the key enzymes involved in glyconeogenesis, in [Lmna.
Ribulose bisphosphate carboxylase
and proteolytic activity in wheat leaves from anthesis through senescence.
Furthermore, the treatment suppressed cardiac overexpression of mRNAs encoding for FA transport protein, peroxisome proliferator-activated receptor (PPAR)-alpha, carnitine palmitoyltransferase-1, acyl-CoA oxidase and 5'-AMP-activated protein kinase alpha2, and restored downregulated cardiac acetyl-CoA carboxylase
mRNA expression in ZDF rats, whereas it showed little effect in Zucker lean rats.
PA results from a deficiency of mitochondrial propionyl-CoA carboxylase
, an enzyme that requires biotin as a cofactor and converts propionyl-CoA to D-methylmalonyl-CoA.
3] J03933 Thrb thyroid hormone receptor beta, c-erbA-[beta] U73174 Gsr glutathione reductase L08447 Cd3z T-cell receptor CD3 zeta subunit L46791 Ces3 liver carboxylase
precursor 10 (carboxylesterase 3) J02650 Rpl19 60S ribosomal protein L19 X96394 Abcc1 multidrug resistance protein D29766 Bcar1 FAK substrate p130 U49062 Cd24 signal transducer CD24 D16554 Ubb polyubiquitin 5 PPM [O.
Comparison of rbcL genes for the large subunit of ribulose-bisphosphate carboxylase
from closely related C3 and C4 plant species.
Effect of limited concentrate feeding on mRNA concentrations of phosphoenol pyruvate carboxykinase (PEPCK), pyruvate carboxylase
(PC), and visfatin in liver by RT-PCR relative to the reference gene (GAPDH) Variable Control (1) Restricted SEM (2) p-value PEPCK-C 0.
According the reports of Karimi and Naderi  in drought stress condition protein's destroyed any Riboluse Bis Phosphat carboxylase
(Rubisco) that is the most frequent protein in plant in deficit irrigation become to decrease .
Phosphorylation of both acetyl CoA carboxylase
and AMP-activated protein kinase was increased, thus explaining the increase in fatty acid oxidation.