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caspase

   Also found in: Acronyms, Encyclopedia, Wikipedia 0.02 sec.
ThesaurusLegend:  Synonyms Related Words Antonyms
Noun1.caspase - any of a group of proteases that mediate apoptosis
peptidase, protease, proteinase, proteolytic enzyme - any enzyme that catalyzes the splitting of proteins into smaller peptide fractions and amino acids by a process known as proteolysis


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In tests with primary T cells or Jurkat T leukemia cells, the extended presence of YopH led to apoptosis through a mitochondria-dependent pathway, as indicated by mitochondrial breakdown, caspase activation, DNA fragmentation, and annexin V binding.
Prevention of immune cell apoptosis as potential therapeutic strategy ... by Bray, Mike / Emerging Infectious Diseases
Idun Pharmaceuticals' IDN-6556 is a liver-targeting caspase inhibitor that prevents apoptosis (cell death).
The hepatitis C drug development pipeline by Raymond, Daniel / Research Initiative/Treatment Action!
Now, a team of researchers has found compounds that inhibit a specific caspase inhibitor, thereby triggering the death of various tumor cells growing in laboratory dishes or in mice.
Compounds trigger tumor-cell suicide by Travis, John / Science News
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