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cathepsin

   Also found in: Medical, Acronyms, Encyclopedia, Wikipedia 0.01 sec.
ca·thep·sin  (k-thpsn)
n.
Any of various proteolytic enzymes found in animal tissue that catalyze the hydrolysis of proteins into polypeptides.

[German Kathepsin, from Greek kathepsein, to digest : kat-, kata-, cata- + hepsein, to boil.]

cathepsin [kəˈθɛpsɪn]
n
(Life Sciences & Allied Applications / Biochemistry) a proteolytic enzyme responsible for the autolysis of cells after death
[from Greek kathepsein to boil down, soften]


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The methods depend upon inhibiting invariant chain proteolysis by cathepsin S from class II MHC/invariant chain complexes, thereby reducing the competency of class II MHC molecules for binding antigenic peptides, reducing presentation of antigenic peptides by class II MHC molecules, and suppressing immune responses.
Among the many cytokines that have been studied in addition to TNF are interleukin 1, interleukin 6, interleukin 17, protein kinases, and most recently a substance called cathepsin G.
Elastonyl combats the degradation of elastic tissue by inhibiting the expression of proteolytic enzymes such as MMP-1, MMP-2 and cathepsin L.
 
 
 
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