K-dependent toll-like receptor 9 signalling revealed in experimental arthritis.
The inheritance is autosomal recessive and the point of mutation is the gene for cathepsin
C (CTCS), a lysosomal protease, which lies on chromosome (11q14-q21).
In all groups, 20 paraffin blocks belonging to the primary tumor in the breast were stained by ICAM-1, VCAM-1, Cyclin D1 and Cathepsin
Ultraviolet A enhances cathepsin
L expression and enzymatic activity
In the phytophagous insect, Colorado potato beetle, molecular complex interactions take place between the insect and the plant observing the "Red Queen hypothesis"; the food protein digestion is initiated by cathepsin
D aspartic peptidase (Brunelle et al.
O'Donoghue, a cardiovascular medicine specialist at Brigham and Women's Hospital, noted in her presentation that "preclinical data suggested that inhibition of cathepsin
K may reduce atherosclerosis progression and promote plaque stability.
6) leupeptin, 1 mM phenylmethylsulfonyl fluoride (PMSF)], and Anally a cathepsin
buffer [50 mM Tris-HCl pH 7.
The report provides comprehensive information on the Cathepsin
S (EC 3.
NFATc1 translocates to the nucleus and induces the expression of multiple osteoclast markers, such as tartrate-resistant acid phosphatase (TRAP), cathepsin
K, and cellular tyrosine protein kinase-Src (c-Src) (Boyle et al.
Rather than focus on a known factor, we did a screen for proteins that could be secreted by muscle tissue and transported to the brain, and among the most interesting candidates was cathepsin
B," says senior author Henriette van Praag, a neuroscientist at the National Institute on Aging in the United States.
However, the DEGs encoding cathepsin
L and CBR1 (carbonyl reductase 1) were down-regulated.
Another proteinase that has been implicated in COPD pathogenesis is cathepsin
S, a lysosomal acidic proteinase which is highly expressed by cells implicated in COPD pathogenesis including macrophages and dendritic cells .