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1. An alkaloid, C9H11NO, that is present in fresh khat leaves and is a central nervous system stimulant. It is a controlled substance in the United States.
2. Any of several synthetic derivatives of this alkaloid that are used as drugs for their stimulating properties.

[New Latin Catha, khat genus (from Arabic qāt, khat; see khat) + -in(e) + -one.]
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Based on the autopsy and toxicological examination conducted on the victims, authorities said they tested positive for a designer drug known as methylenedioxymethamphetamine or MDMA methylene homolog and methylenedixy cathinone.
Its psychotropic elements are two alkaloids, cathinone and cathine, which are stimulants, according to Live Science .
24 (BNA): His Royal Highness Prince Khalifa bin Salman Al Khalifa the Prime Minister issued Edict 39/2016 amending the lists of anesthetic and narcotic substances associated with Law 15/2007, adding synthetic cannabinoids, synthetic cathinone, Tramadol, Ketamine and Apaan (alpha-phenylacetoacetonitrile) to the lists, and tasking the ministers each according to their domain to implement this Edict effective from the day following the date of its publication in the Official Gazette.
Cathinone is believed to be the main active ingredient in fresh khat leaves and is structurally related and pharmacologically similar to amphetamine.
The first occurred in a male aged 17 years, who suffered a cardiac arrest after reportedly taking a single "hit" of K2/Spice; the second occurred in an adult male with respiratory depression, agitation, and delirium/toxic psychosis after allegedly taking a synthetic cannabinoid and oxycodone; and the third occurred in an adult male with similar signs, who developed acute kidney injury after reportedly taking a synthetic cannabinoid, a synthetic cathinone (commonly known as bath salts), and the psychedelic drug lysergic acid diethylamide (LSD).
This edition has updated and new content, discussion of new synthetic cannabinoids and cathinone derivatives, more on the functional and molecular pharmacology of cocaine and myocardial remodeling, more on deaths related to prescription medications, suggestions on the interpretation of postmortem drug measurements, new high-resolution full-color micrographs, and new appendices on standard reference values.
Mephedrone, also known as Meow, Bubbles and MCAT, is derived from cathinone, a compound found in a plant called Khat.
Another major threat to the industry is the increasing production of qat, a flowering plant that contains cathinone, an amphetamine-like stimulant, which is consumed by users for recreational use.
The new drug's slick website, which we are also not identifying, boasts to its potential customers: "When the generic cathinone [Meow Meow] ban came in we thought we may never see another UK legal cathinone hit the market.
Prof Thomas continued: "Use of new psychoactive substances became increasingly widespread about five years ago, when the use of cathinone drugs such as methadone became increasingly common.
Five months later, khat ingredients cathine and cathinone were banned in competition by the World Anti-Doping Agency.
Cathinone is naturally found in the khat plant and has been used by people for hundreds of years for its mild stimulant properties.