All MRSA pathogens showed susceptibility to vancomycin (100%) imipenem (81%) and doxycycline (55%) but were found highly resistant to cefpirome and erythromycin (98%) clarithromycin chloramphenicol and ciprofloxacin (93%) fosfomycin fusidic acid and trimethoprim/ sulphamethoxazole (83%) sulbactam/ cefoperazone
(81%) clindamycin (76%) amikacin (67%) and piperacillin / tazobactam (60%) as shown in Table-III.
Patients were divided into five groups Group I No Antibiotics, Group II Ampicillin / Gentamicin / Metronidazole, Group III Ceftriaxone / Metronidazole, Group IV Ampicillin / Sulbactum, Group V Cefoperazone
Various antimicrobial agents ([micro]g) used were amikacin (30), gentamicin (10), tobramycin (10), ceftazidime (30), ceftriaxone (30), ceftizoxime (30), cefoperazone
(75), carnbenicillin (100), piperacillin (100), Ticarcillin (75), ciprofloxacin (5), lomefloxacin (10) and imipenem (10) (Hi-media, Mumbai, India).
Escherichia coli, Klebsiella pneumoniae and Pseudomonas aeruginosa showed high sensitivity to Carbapenem and Piperacillin Tazobactam and Cefoperazone
75 g) gentamycin (10 g) meropenem (10 g) imipenem (10 g) piperacillin-tazobactam (100/10 g) and sulbactam- cefoperazone
(75/30 g) were placed on Mueller- Hinton agar plates and incubated overnight at37oC.
The bacterial culture was positive for Staphylococcus aureus with sensitivity to (Ciprofloxacin, Ofloxacin, Amikacin, Azithromycin, Gatifloxacin, Tobramycin, and Enrofloxacin) and resistant to (Norfloxacin, Cefoperazone
, Cefotaxime, Cephalexin, Ampicillin, Erythromycin, Cefuroxime and Gentamycin).
Limited Tenders are invited for Supply Of Expendable Medical Stores:Inj Cefoperazone
sod1gm & Sulbactum sod 1gm,Inj Human Chorionic Gonadatropin
62% for doxycycline and 50% for ceftriaxone and Cefoperazone
/ tazobactam sodium injection (14.
0% resistance to cefuroxime, cefotaxime, and cefoperazone
3, 4, 5) Cefoperazone
is available as a co-formulation with Sulbactam.
The relevant drugs which affected approximately 97% of our isolates were two injectables - Pipericillin and the 3rd generation Cephalosporin Cefoperazone
- both endowed with enhanced activity because of the addition of the beta-lactamase inhibitors Tazobactam and Sulbactam, respectively.