A disc containing 30[micro]g amoxicillin-clavulanate (Oxoid, England) was placed at the centre of the agar plate close to a 30[micro]g ceftazidime
disc (30mm apart).
In eEDST, IPM disc synergy could identify 20 isolates; meropenem (MEM) disc synergy identified 18 while ceftazidime
(CAZ) disc synergy could detect only 12 isolates as MBL producers.
2 mg/kg/day and with IV ceftazidime
, amoxicillin/clavulanate, and metronidazole.
Both biotypes were resistant to ceftazidime
and susceptible to imipenem.
These included ceftazidime
, ciprofloxacin, levofloxacin, imipenem, trimethoprim-sulfamethoxazole, amikacin, gentamicin, chloramphenicol, cefepime, and piperacillin-tazobactam.
make special note of drugs related to the antibiotic cephalosporin -- including cefotaxime, cefoxitin, ceftizoxime, ceftriaxone, cefotetan and ceftazidime
Susceptible strains were defined as having a ceftriaxone MIC [less than or equal to]1 mg/L, ceftazidime
MIC [less than or equal to] 4 mg/L, azithromycin MIC [less than or equal to]16 mg/L, and imipenem MIC [less than or equal to] 2 mg/L.
The antibacterial, synergy effects and primary mechanism of action of galangin and ceftazidime
The disks containing the following antibiotics ([micro]g) were used (Beckton Dickinson): cefoxitin (30), cefepime (30), ceftazidime
(30), cefotaxime (30), ertapenem (10), imipenem (10), amikacin (30), gentamicin (10), ciprofloxacin (5) and chloramphenicol (30).
, meropenem, amikacin, and cefepime were the most effective antibiotics, especially against Pseudomonas aeruginosa, in which resistance rates ranged from 3% to 5%.
, or, less often, piperacillin or aztreonam).
NASDAQ: CBST), a leading acute care therapeutics company, today announced that the recently-completed Phase 2 study of CXA-101, a novel cephalosporin, compared to ceftazidime
for the treatment of complicated urinary tract infections (cUTI) in adults met its study objectives.