celecoxib


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cel·e·cox·ib

 (sĕl′ə-kŏk′sĭb)
n.
A nonsteroidal anti-inflammatory drug, C17H14F3N3O2S, that selectively inhibits the formation of prostaglandins and is used primarily to treat pain and other symptoms of osteoarthritis, rheumatoid arthritis, and other joint and musculoskeletal conditions.

[Alteration of sele(ctive) + COX(-2 inh)ib(itor).]

celecoxib

(ˌsɛləˈkɒksɪb)
n
an anti-inflammatory drug
ThesaurusAntonymsRelated WordsSynonymsLegend:
Noun1.celecoxib - a Cox-2 inhibitor (trade name Celebrex) that relieves pain and inflammation without harming the digestive tract
Cox-2 inhibitor - an anti-inflammatory drug that fights pain and blocks Cox-2 activity without impeding the activity of Cox-1; increases the risk of heart attacks; "Cox-2 inhibitors reduce the symptoms of arthritis without endangering the stomach and kidneys"
Translations

celecoxib

n celecoxib m
References in periodicals archive ?
Summary: A high performance liquid chromatographic method was developed and validated to simultaneously quantify citalopram with piroxicam, celecoxib and diclofenac sodium.
PRECISION-ABPM, a four-month sub-study of the Cleveland Clinic-led PRECISION trial, evaluated the blood pressure effects of prescription ibuprofen (Advil[R], Motrin[R]), naproxen (Aleve[R]) and celecoxib (Celebrex[R]) among 444 patients, average age 62, with arthritis who had heart disease or were at increased risk for it.
Chondroitin Sulfate Similar to Celecoxib for Osteoarthritis of the Knee
The researchers conducted animal studies tracking the effects of celecoxib on the growth of cancer cells from a tumour type known as neurofibromatosis type II (NF2).
BARCELONA -- Prescription-strength ibuprofen has a bigger adverse effect on blood pressure than celecoxib or naproxen, a finding that suggests a likely mechanism for the worse cardiovascular event rate documented in ibuprofen-treated arthritis patients in the PRECISION trial, Frank Ruschitzka, MD, said at the annual congress of the European Society of Cardiology.
BARCELONA--Prescription-strength ibuprofen has a bigger adverse effect on blood pressure than celecoxib or naproxen, a finding that suggests a likely mechanism for the worse cardiovascular event rate documented in ibuprofen-treated arthritis patients in the PRECISION trial, Frank Ruschitzka, MD, said at the annual congress of the European Society of Cardiology.
Ibuprofen is associated with increased blood pressure and hypertension compared to celecoxib in patients with osteoarthritis or rheumatoid arthritis and increased risk of cardiovascular disease, according to late-breaking results from the PRECISION-ABPM study presented today in a Hot Line LBCT Session at ESC Congress (1) and published in EHJ.
Researchers discovered that treating mice with a common anti-inflammatory drug called celecoxib promoted stem cell survival and healing when they injected the cells into wounds.
According to Marina Biotech, IT-102, a celecoxib and lisinorpril FDC, is being developed for the combined treatment of arthritis and hypertension.
Celecoxib (Celebrex) is a COX-2 inhibitor that is an effective pain reliever for many patients who have arthritis.
1) Traditional NSAIDs (tNSAIDs), such as aspirin, ibuprofen, naproxen, and diclofenac, represent an effective, long-lasting option that may offer advantages over cyclooxygenase-2 (COX-2) selective NSAIDs, such as celecoxib.
While two others in its class of drugs, Vioxx and Bextra, were removed from the market in 2004 and 2005, respectively, celecoxib (Celebrex) remains available, but with a black box warning that it carries the risk of heart attack and stroke.