Working with experts from Sweden, Germany and USA, they have discovered mechanisms that control a new form of premature cell death
in living tissue - called ferroptosis - and a way to reverse it.
The U-M study, which looked at the use of antimicrobials to fight cancerous tumors, suggests nisin, in part, slows cell proliferation or causes cell death
through the activation of a protein called CHAC1 in cancer cells, a protein known to influence cell death
Among the topics are the origins and evolution of programmed cell death
, caspases and cell death
, mitochondrial outer membrane permeabilization, death receptors, the engulfment of apoptotic cells and its physiological roles, autophagy, regulatory genes and disease, cornification of the skin as a non-apoptotic cell death
mechanism, inherited disorders, and microbial inhibitors of apopotosis.
Alternatively, the composition can contain at least one agent that promotes T cell death
and at least one agent that inhibits T cell proliferation.
Trivalent forms of arsenic have been found to induce apoptosis in several cellular systems with involvement of membrane-bound cell death
receptors, activation of caspases, release of calcium stores, and changes of the intracellular glutathione level.
Previous work with rodents and other animals led scientists to theorize that the postinjury flood of glutamate contributes to the delayed cell death
by overstimulating nerve cells.
Neuronal cell death
has been shown to occur by apoptotic, necrotic and so-called atypical cell death
occurs rapidly via a novel mechanism-of-action that does not require a fully functioning immune system.
The purpose of this study is to determine whether AGE inhibits cell death
induced by SAM in PC12 cells.
We report that the WNV capsid (Cp) by itself induces rapid nuclear condensation and cell death
in tissue culture.
Motoneurons appears to die by apoptotic cell death
during this time, different from necrotic cell death
Dr Tomaselli described how, by applying Idun's established expertise in developing modulators of programmed cell death
, it would be possible to extend the lifespan of engineered cell lines and thereby enhancing productivity and reducing manufacturing costs.