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cytotoxicity |
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The resulting product is expected to have target specificity similar to Rituximab (Rituxan([R]), Mabthera([R])) and to have relatively higher antibody dependent cell-mediated cytotoxicity, or ADCC. Role of antibody-dependent cell-mediated cytotoxicity in the efficacy of therapeutic anti-cancer monoclonal antibodies. nbsp;of the antibody has been shown in previous studies to be responsible for mediating antibody-dependent cell-mediated cytotoxicity and has been the target of Xencor's XmAb technology. |
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