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cell-mediated immune response

   Also found in: Medical, Acronyms, Encyclopedia, Wikipedia 0.01 sec.
cell-med·i·at·ed immune response  (slmd-td)
n.
The immune response produced when sensitized T cells directly attack foreign antigens and secrete lymphokines that initiate the body's humoral immune response. Also called cellular immune response.

cell-mediated immune response
An immune response produced when T cells, especially cytotoxic T cells, that are sensitized to foreign antigens attack and lyse target cells. In addition to direct cytotoxicity, T cells can stimulate the production of lymphokines that activate macrophages. Cell-mediated immune responses are important in defense against pathogens, autoimmune diseases, some acquired allergies, and other immune reactions.
ThesaurusLegend:  Synonyms Related Words Antonyms
Noun1.cell-mediated immune response - an immune response (chiefly against viral or fungal invasions or transplanted tissue) that involves T cells
immune reaction, immune response, immunologic response - a bodily defense reaction that recognizes an invading substance (an antigen: such as a virus or fungus or bacteria or transplanted organ) and produces antibodies specific against that antigen


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receptor blocking agents are useful for treating lymphocyte-mediated immunological diseases, and more particularly, for inhibiting Th1 cell-mediated immune responses.
5) An intact immune system is essential for the development of a positive skin test; conversely, any impairment of the cell-mediated immune response generally results in a minimal or absent reaction and thus a negative test.
The scientists have not yet evaluated the cell-mediated immune response in the volunteers, nor whether their antibodies can neutralize HIV in vitor.
 
 
 
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