centromere


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cen·tro·mere

 (sĕn′trə-mîr′)
n.
The most condensed and constricted region of a chromosome, to which the spindle fiber is attached during mitosis.

cen′tro·mer′ic (-mĕr′ĭk, -mîr′-) adj.

centromere

(ˈsɛntrəˌmɪə)
n
(Genetics) the dense nonstaining region of a chromosome that attaches it to the spindle during mitosis
centromeric adj

cen•tro•mere

(ˈsɛn trəˌmɪər)

n.
a structure appearing on the chromosome during mitosis or meiosis, where the chromatids are joined in an X shape.
[1920–25]
cen`tro•mer′ic (-ˈmɛr ɪk, -ˈmɪər-) adj.

cen·tro·mere

(sĕn′trə-mîr′)
The region of the chromosome to which the spindle fiber is attached during mitosis. The centromere is where the chromatids join together in pairs before separating into individual chromosomes. See more at meiosis, mitosis.
ThesaurusAntonymsRelated WordsSynonymsLegend:
Noun1.centromere - a specialized condensed region of each chromosome that appears during mitosis where the chromatids are held together to form an X shape; "the centromere is difficult to sequence"
anatomical structure, bodily structure, body structure, complex body part, structure - a particular complex anatomical part of a living thing; "he has good bone structure"
chromosome - a threadlike strand of DNA in the cell nucleus that carries the genes in a linear order; "humans have 22 chromosome pairs plus two sex chromosomes"
Translations
centrómero
tsentromeer
References in periodicals archive ?
One of the reasons for this intensive clustering phenomenon may be the higher sensitivity of the AFLP technique because the degraded recombination rate near centromere or telomere, non - equal of restriction enzyme sites and high repeat factor could cause these intensive clustering markers (Strommer et al.
They result from two terminal breaks on both chromosome arms followed by fusion of the broken ends containing the centromere to form a circular structure leading to the loss of genetic material.
Increased CEP17 copy number may occur because of a focal gain in the centromeric region, polysomy (a duplication of the entire chromosome), a gain of a large portion of chromosome 17, or coamplification of the centromere and HER2.
0 mg/dL Centromere type HTLV-1 (-) Nucleolar type IgG (800~1700) 1036 mg/dL Peripheral type Ig A (100~400) 143 mg/dL Granulartype IgM (40~240) 108 mg/dL Total cell count of bronchoalveolar lavage fluids IgE (20~140) 32 mg/dL RF(<10.
We recently identified the triggering event in centriole biogenesis and how its regulation is akin to cell cycle control of DNA replication and centromere assembly.
Prior to anaphase, the CPC is highly enriched at the inner centromere, and ABK activity contributes to spindle and kinetochore assembly, spindle assembly checkpoint signaling, and error correction (Tanaka et al.
Laboratory studies showed a positive ANA >1:2,560 with a centromere pattern, negative Scl-70, and positive antimitochondrial antibody at 158.
Further subdivision of translocation types can be made according to the exchange of chromosomal material and are classified as: (i) reciprocal, when segments from two different chromosomes have been exchanged; or (ii) robertsonian, in five acrocentric chromosomes (13, 14, 15, 21 and 22), where long arms fuse to form a single chromosome with a single centromere.
The chromosomes were classified as metacentric, submetacentric, acrocentric or telocentric based on the ratio between the arms (r) and centromere index (ic), which was proposed by Guerra (1986).
This includes pervasive transcription of the genome, conservation of many nonprotein-coding sequences, sequence-dependent functions of RNAs transcribed from introns, pseudogenes, repetitive DNA, functions almost independent of the exact nucleotide sequence, chromatin topology in gene expression and centromere placement, and the light-focusing property of heterochromatin in inverted nuclei.
ANA anti dsDNA anti LKM Anti-SMA AMA C-ANCA P-ANCA anti-SSA anti-SSB anti-Scl-70 anti Jo-1 anti-U1snRNP anti- centromere anti-Jo-1 anti tpo and anti tg were studied in all individuals in each study group.
Secondly complete antibody screening of these patients could not be done even though it is known that a few clinical features of scleroderma are influenced by presence or absence of anti centromere and anti-Scl 70 antibody.