Concentrations of tumor necrosis factor-a, interleukin 6 (IL-6), IL-12/23p40, IL-8, monocyte chemotactic
protein 1, ILIRa, soluble CD40L (sCD40L), IL-15, interferon-g (IFN-g), IL-4, and IL-17 were determined for all samples by using the Bio-Plex 200 System (BioRad Laboratories, Hercules, CA, USA).
Differential effect of saturated and unsaturated free fatty acids on the generation of monocyte adhesion and chemotactic
factors by adipocytes: dissociation of adipocyte hypertrophy from inflammation.
CRP is chemotactic
for monocytes (9) and avidly binds to human neutrophils.
In the obese state, the expression of adipocytokines such as resistin, interleukin-6 (IL-6), tumor necrosis factor-[alpha] (TNF-[alpha]), plasminogen activator inhibitor-1 (PAI-1), monocyte chemotactic
protein-1 (MCP-1), and angiotensinogen is increased in enlarged adipocytes, causing insulin resistance and metabolic disorders.
The patent contains both composition of matter and method claims surrounding therapeutic chemotactic
hematopoietic stem cell products used in treating or repairing a vascular injury following an acute myocardial infarction (AMI), and delivery of the cell therapy.
MCP-1 is a secreted C-C chemokine, having a strong chemotactic
activity on inflammatory cells (5) that mediate the recruitment of blood monocytes into the vessel wall, one of the earliest events in atherosclerosis.
After stimulation with Zymosan[R], blood samples were analysed for elastase and after stimulation by LPS/super-antigen SEB, blood samples were analysed for interleukin-1 [beta] (IL-1[beta]), IL-6, IL-8, IL-10, IL-12, macrophage chemotactic
protein-1 (MCP-1), tumor necrosis factor a (TNF-[alpha]) and interferon-[gamma] (IFN-[gamma]).
C5a, through binding to its receptor C5aR, induces expression of additional adhesion molecules and chemotactic
factors, thus perpetually amplifying the destructive inflammatory cascade.
As thymol, one of the major components of thyme oil with a phenolic structure, has been credited with a series of pharmacological properties, that include antimicrobial and antioxidant effects, the aim of this study was to explore whether it can also interfere with the release of elastase by human neutrophils stimulated with the synthetic chemotactic
peptide N-formylmethionyl-leucyl-phenylalanine (fMLP).
Interleukin-8 (IL-8): the major neutrophil chemotactic
factor in the lung.
Leukocytes are attracted to the injury site by chemotactic
proteins known as chemokines, which are secreted by endothelial cells of the blood vessels.
Further molecular analyses demonstrated that IMMUNITIN down-regulates inflammatory mediator genes, including Interleukin 1(beta) gene (IL-1(beta)), Interleukin 6 gene (IL-6), Macrophage Chemotactic
Protein 1 gene (MCP1), inducible-Nitric Oxide Synthase gene (iNOS), responsible for the generation of nitric oxide (NO), and Matrix Metalloprotease 9 gene (MMP9), involved in tissue destruction and bone remodeling.