In particular, these putative pESCs do not form teratomas or display germ-line chimerism
One of these patients achieved full donor CD3 chimerism
(engraftment of donor cells) after one year of IMBRUVICA treatment and has maintained undetectable CLL MRD for more than 10 months after stopping therapy.
In contrast to transplantation for malignancies, mixed chimerism
in haemoglobinopathies therefore does not necessarily mean treatment failure.
could also be caused by fusion of the polar body and an ovum, double fertilization, fusion of two nuclei or as a result of hidden mosaicism with a Y cell line.
1 Rating chimerism
performed in patients undergoing allogeneic transplantation using the method fragment length analysis using a set of AmpFISTR NGM sequencer.
describes the coexistence of DNA or cells originating from more than one individual.
Even in (1) the case of identical twins that originate from a single zygotic cell that divides into two distinct beings, or (2) the case of tetragametic chimerism
in which two originary zygotic cells fuse into one, the human soul--as nonspatial--can be regarded as united with the distinct material body at its inception.
Radiation therapy, chimerism
, infection or vaccination, drugs, trauma, hormones and genetic factors are implicated in the etiology.
may be promoted in hand transplant patients by giving the recipient donor bone marrow or via the production of immune precursor cells in vascularized donor bone marrow.
Aiding in the identification of mosaic aneuploidy and chimerism
Origin and outcome of pregnancies affected by androgenetic/biparental chimerism
and Tetragametic Chimerism
in Humans: Implications in Autoimmunity, Allorecognition, and Tolerance," Immunology Research 38 (2007) 213-36.