In addition, the 12 PCB congeners with dioxin-like (coplanar) structure (ATSDR 2000) are known to cause a broad range of adverse health effects ranging from simple chloracne
to serious reproductive abnormalities and immune deficiencies (Schecter et al.
Just what did take place was that the detainees created an eruption of chloracne
(all that things from high school integrated with blackheads and cysts and pustules that gave the appearance of the photo shown to the left) that stem on the cheeks, behind the ears, armpits, and the groin-- of course, the groin.
51,52) TCDD also has other, Nrf2-independent toxic effects, but these acne-like changes in skin properties are clearly caused by excessive, long-term levels of Nrf2, such that chloracne
may serve as a marker for excessive Nrf2 stimulation.
Category of Evidence Presumption Examples Sufficient evidence of an B-cell leukemia association Chloracne
Limited/suggestive evidence of Prostate cancer an association Diabetes Inadequate/insufficient evidence 1994 assessment for type II to determine whether an diabetes, moved to limited/ association exists suggestive in 2000.
Non-cancer effects of exposure to large amounts of dioxin include chloracne
, developmental and reproductive effects, damage to the immune system, interference with hormones, skin rashes, skin discoloration, excessive body hair, and possibly mild liver damage.
Common differential diagnoses include infantile acne, familial dyskeratotic comedones (FDC), extensive comedones due to chloracne
and sun damage, dilated pore nevus and porokeratotic eccrine ostial duct nevus.
In humans, exposure to dioxins has been linked to a variety of adverse effects, including chloracne
(Baccarelli et al.
Between June 1, 1966 and June 30, 2011 the applicant must have been diagnosed for one of the following prescribed medical conditions: CLC, soft tissue sarcoma, Hodgkin's disease, chloracne
, respiratory or prostate cancer, myeloma, transient peripheral neuropathy, porphyria cutanea tarda, type 2 diabetes or spinal bifida.
Additionally, exposure to PCDDs and PCDFs has been linked to myeloid leukemia, chloracne
, hemorrhaging, and carcinogenic effects, as well as promoting increased risk of cardiovascular and respiratory diseases (Bertazzi et al.
or other acneform disease consistent with chloracne
The conditions the Department of Veterans Affairs recognizes on this basis are soft-tissue sarcoma, non-Hodgkin's lymphoma, chloracne
, Hodgkin's disease, porphyria cutaneatarda (PCT), multiple myeloma (a cancer involving the bone marrow), and respiratory cancers (lung, bronchus, larynx, and trachea).
About how the government long denied that exposure to Agent Orange could contribute to any ill-health except a case of chloracne
, a disfiguring skin condition.