M2 PHARMA-March 1, 2018-Durect Initiates Patient Dosing in Phase 2a Trial of DUR-928 in Primary Sclerosing Cholangitis
The FDA this morning is warning that Intercept Pharmaceuticals' liver disease medicine Ocaliva has been incorrectly dosed daily instead of weekly in patients with moderate to severe primary biliary cholangitis
, a rare chronic liver disease, increasing the risk of serious liver injury.
JANE ROBERTS: British Heart Foundation, Cancer Research and Primary Sclerosing Cholangitis
(PSC) Support, as they have all helped my family.
Concurrently, the company is currently evaluating Saroglitazar in several clinical trials for treating liver conditions like NASH and Primary Biliary Cholangitis
Immunoglobulin G4 (IgG4)-related cholangitis
(IAC) is one of the IgG4-related immune-mediated diseases.
While multiple options exist for the treatment of pruritus in patients with primary biliary cholangitis
(PBC), none have compelling evidence regarding long-term efficacy and safety, according to a literature review, by Hirsh D.
SUMMARY--We report a case of biliary cyst type II which, independently of its a priori benign nature, caused numerous complications such as recurrent cholangitis
and pancreatitis, as well as subsequent hepatic fibrosis and the potential danger of choledochocele perforation.
Immediate examination by multiple specialists - an intensivist, a nephrologist, a cardiologist and an anesthesiologist determined that it was necessary to conduct ERCP to treat the cholangitis
, else the patient's condition could prove fatal.
Aaron, who is orginally from Omagh, Co Tyrone, was diagnosed with ulcerative colitis at 14 and five years later doctors discovered he had primary sclerosing cholangitis
, an uncommon chronic liver disease.
Background and Objective: Biliary cysts in pregnant women are a complex medical issue, especially when complicated with cholangitis
Long term success was the absence of anastamotic stricture, no episode of cholangitis
and no emergence of cholangiocarcinama.
Phase 2 studies with GS-9674 are ongoing in patients with NASH, primary biliary cholangitis
(PBC) and primary sclerosing cholangitis