5) The differential diagnosis includes cholesterol granuloma
, aberrant carotid artery, and tumors such as paraganglioma or schwannoma.
is a benign, non-specific inflammatory fibrogranulomatous lesion that develops secondary to a foreign body reaction to cholesterol crystals.
is a histopathologic term describing a large number of clefts present after cholesterol crystals have dissolved during processing, with surrounding foreign-body giant cells, foam cells, and macrophages filled with hemosiderin embedded in fibrous granulation tissue.
5) Occasionally, a cholesterol granuloma
will demonstrate an area of hypointensity on MRI as a result of a solid mineral content within the cyst.
We report the unique finding of a petrous apex cholesterol granuloma
associated with a paraganglioma, also known as a glomus jugulare tumor, in a 52-year-old woman who presented to our department with pulsatile tinnitus, hearing loss, aural fullness, and disequilibrium.
Hemotympanum has many causes, including temporal bone fractures, barotrauma, administration of anticoagulants, hematologic disorders, and chronic otitis media secondary to the formation of granulation tissue or a cholesterol granuloma
The MRI identified the posterior lesion as a cholesterol granuloma
and the anterior mass as a cholesteatoma pearl (figure 2, A).
Extradural cholesteatomas must be differentiated from squamous cell carcinoma (which has malignant squamous epithelium) and cholesterol granuloma
(which contains cholesterol clefts).
Culture and histology of the sinus contents detected evidence of a cholesterol granuloma
but no fungal material.
They are especially helpful for chronic mucoid otitis media, which if not treated with a ventilation tube can progress along a continuum leading to chronic otitis media and chronic mastoiditis characterized by granulation tissue, cholesterol granuloma
, and/or cholesteatoma.
in the absence of physical trauma to the membrane) or in association with chronic otitis media as a result of the formation of granulation tissue or a cholesterol granuloma
Without a supportive history, a blue eardrum in the presence of a cholesterol granuloma
can make the differential diagnosis difficult.