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Related to cholinergic: acetylcholine, anticholinergic, Cholinergic crisis, cholinergic urticaria, Cholinergic Drugs, cholinergic receptors


1. Activated by or capable of liberating acetylcholine, especially in the parasympathetic nervous system.
2. Having physiological effects similar to those of acetylcholine: a cholinergic agent or drug.

[(acetyl)cholin(e) + -ergic.]

cho′li·ner′gi·cal·ly adv.


1. (Physiology) denoting nerve fibres that release acetylcholine when stimulated
2. (Physiology) of or relating to the type of chemical activity associated with acetylcholine and similar substances
[C20: from (acetyl)cholin(e) + Greek ergon work]


(ˌkoʊ ləˈnɜr dʒɪk, ˌkɒl ə-)

1. resembling acetylcholine in physiological effect: a cholinergic drug.
2. releasing acetylcholine: a cholinergic neuron.
3. activated by acetylcholine: a cholinergic receptor.
[1930–35; (acetyl) choline + -ergic]
ThesaurusAntonymsRelated WordsSynonymsLegend:
Adj.1.cholinergic - releasing or activated by acetylcholine or a related compound
anticholinergic - inhibiting or blocking the action of acetylcholine at a receptor site; "anticholinergic drugs"
References in periodicals archive ?
Contract award: tender for the supply of tiotropium bromide powder for inhalation "spiriva" for treatment with cholinergic antagonist negotiated procedure without notice contest (ddchpd.
Michael Mullan, MBBS, PhD, Chairman and CEO of Rock Creek Pharmaceuticals, will present preclinical and clinical data for anatabine citrate, a small molecule cholinergic agonist which exhibits anti-inflammatory pharmacological characteristics.
Their mechanism of action for cholinergic enhancement is suboptimal, and they do not repair neurons, protect against death, or truly restore lost neuronal function.
Indeed, cholinergic manipulations may affect specific types of memory and may depend on different brain structures (29).
The results of the present study provide a new possibility that endogenous neurotoxins (R)-Sal and (R)NMSal not only affect the dopaminergic system by inhibiting the related enzymes in the synthesis or metabolism of DA, but also impair the cholinergic system by inactivating AChE.
At high doses, inhibition of cholinesterase leads to cholinergic hyperstimulation and its associated symptoms (Mileson et al.
Since diminished cholinergic transmission and increase cholesterol levels appear to be responsible for development of amyloid plaques and dementia in Alzheimer patients, this may prove to be a useful medicine in humans.
University of California (Oakland, CA) has patented a specific clinical protocol for use toward therapy of defective, diseased and damaged cholinergic neurons in the mammalian brain, of particular usefulness for treatment of neurodegenerative conditions such as Alzheimer's disease.
Botulinum toxin, which causes temporary chemical denervation of the cholinergic nerve fibers, has also been used successfully to manage sialoceles.
There is evidence from our studies and from other, smaller studies that behavioral symptoms can improve with cholinergic treatment," said Dr.
KEY WORDS: Alzheimer's disease; chronic AODE (effects of alcohol or other drugs); AODR (alcohol or other drug-related) dementia; risk factors; cognitive and memory disorder; cholinergic receptors; drug interaction; alcoholic beverage; nicotine; diagnostic criteria; disease course; survey of research