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cholinergic
(redirected from cholinergic receptors)

   Also found in: Medical, Legal, Encyclopedia, Wikipedia 0.01 sec.
cho·li·ner·gic  (kl-nûrjk)
adj.
1. Activated by or capable of liberating acetylcholine, especially in the parasympathetic nervous system.
2. Having physiological effects similar to those of acetylcholine: a cholinergic agent or drug.


choli·nergi·cal·ly adv.

cholinergic [ˌkəʊlɪˈnɜːdʒɪk]
adj
1. (Life Sciences & Allied Applications / Physiology) denoting nerve fibres that release acetylcholine when stimulated
2. (Life Sciences & Allied Applications / Physiology) of or relating to the type of chemical activity associated with acetylcholine and similar substances
[from (acetyl)cholin(e) + Greek ergon work]

cholinergic  (kl-nûrjk)
1. Relating to a neuron or axon that is activated by or is capable of releasing acetylcholine when a nerve impulse passes. The nerve endings of the parasympathetic nervous system are cholinergic.
2. Having physiological effects similar to those of acetylcholine, as certain drugs.
ThesaurusLegend:  Synonyms Related Words Antonyms
Adj.1.cholinergic - releasing or activated by acetylcholine or a related compound
anticholinergic - inhibiting or blocking the action of acetylcholine at a receptor site; "anticholinergic drugs"


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Chapter topics include: the role of prefrontal cholinergic receptors in the pathology of schizophrenia; participation of the prefrontal cortex in the processing of sexual and maternal incentives; the orbitofrontal cortex and emotional decision-making; the role of the prefrontal cortex in cognitive impairment in Parkison's disease, and noradrenergic actions in prefrontal cortex as they relate to AD/HD.
In secondary measures of outcomes, the 5-mg twice-daily dose of asenapine significantly lowered scores, compared with placebo, on subscales assessing positive symptoms, negative symptoms, and general psychopathology Asenapine binds to several serotonergic, dopaminergic, and a-adrenergic receptors, but has almost no affinity for muscarinic cholinergic receptors, and so is assumed to cause fewer significant anticholinergic side effects, compared with other antipsychotic medications.
The phosphorylated AChE cannot break down ACh and accumulation of acetylcholine in the synaptic cleft causes excess stimulation at cholinergic receptors throughout the central and peripheral nervous system.
 
 
 
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