chondrocyte


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chon·dro·cyte

 (kŏn′drə-sīt′)
n.
A cartilage cell located in a lacuna of the cartilage matrix.
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a scientific founder of NeoCart, Assistant Professor, Orthopedic Surgery, Brigham and Women's Hospital, and Harvard Medical School, will deliver a podium presentation on NeoCart, entitled, "Platform Technologies for the Third Generation of Autologous Chondrocyte Implantation".
Based on this background, it is proposed as a contraindication to apply therapeutic US in pediatric patients in areas close to the PC, since it could cause a premature closure of the plaque or alterations in the chondrocyte maturation (Cameron).
Chondrocyte proliferation has been typically considered as the major contributor of longitudinal growth.
Increased proteoglycan and cartilage turnover (and decreases in their synthesis), increased chondrocyte apoptosis and chondrocyte depletion have been observed as results (34-37).
Additionally, when measuring cell viability of chondrocytes, intermediate riboflavin concentration may be preferred for cell viability while pH variations did not have an effect on chondrocyte viability.
Chondrocyte has a key role in the process on cellular basis.
Preliminary data from in vivo testing over 60 days show the combination does indeed encourage chondrocyte and cartilage production.
Breakdown of the pericellular matrix exposes the chondrocyte membrane to the type II collagen characteristic of articular cartilage, activating and augmenting the expression of the transmembrane discoidin-containing domain receptor 2 (DDR2) [25].
Clinical outcome, return to sport, and long-term durability have been reported to be most satisfying following autologous chondrocyte implantation (ACI) when compared to other techniques [1].
After allogenic MSCs were injected intraarticularly into the rat knee joints, toluidine blue staining in the 4-week group revealed less cartilage degradation, including chondrocyte aggregation on the concave surface of the cartilage, cartilage fissure, and reduced cartilage matrix staining on the therapy sides of the knee joint in both the immobilized and nonimmobilized subgroups [Figure 4]a1 and [Figure 4]a3 compared with the control sides, which exhibited reduced cartilage thickness and superficial cartilage erosion [Figure 4]a2 and [Figure 4]a4.
Lacunae decreased in size compared to an eight-day old newborn, adjusting more to the size of the chondrocyte.