Proper mitosis, in turn, depends on changes in chromosome organization, such as chromosome condensation and sister chromatid
1996) and sister chromatid
exchanges (Olvera-Bello et al.
segregation, called random chromatid
segregation and maximum equational
Types of structural chromosomal aberrations were classified into following groups: chromatid
breaks (ctb) chromosome breaks (csb), chromatid
and chromosomal gap (ctg) The final results were judged as follows: negative (-) if the frequency of aberrant cells was <5%, inconclusive ([+ or -]) if [greater than or equal to]5 % but <10 % and positive (+) if [greater than or equal to] 10 %.
Reduced expression of MAD2, BCL2, and MAP kinase activity in pig oocytes after in vitro aging are associated with defects in sister chromatid
segregation during meiosis II and embryo fragmentation after activation.
503 Establishment of sister chromatid
cohesion and coupling to DNA replication process -0.
The lipid peroxidation end-products malondialdehyde (MDA) and 4-hydroxy-2-nonenal (HNE) adversely affect genome integrity, causing DNA strand breaks, formation of DNA adducts, increased frequency of sister chromatid
exchange, and apoptosis (5,6).
For example, small autosomes presenting double breaks on the same chromatid
and others showing gaps in both chromatids
can be appreciated in Figure 2 B and D.
Among the topics are dormant replication origins, break-induced DNA replication, the mini-chromosome maintenance replicative helicase, the spatial and temporal organization of DNA replication in bacteria and eukarya, DNA replication timing, replication-fork dynamics, sister chromatid
cohesion, translesion DNA polymerases, rescuing stalled or damaged replication forks, genome instability in cancer, regulating DNA replication in plants, endoreplication, the archaeology of eukaryotic DNA replication, human mitochondrial DNA replication, whether human papillomavirus infections are warts or cancer, and adenovirus DNA replication.
Furthermore, some authors have examined the sister chromatid
exchange (SCE) frequencies in BD patients to understand the genetic mechanism.
High frequencies of telomeric associations, chromosome aberrations, and sister chromatid
MX also induced a wide variety of DNA damage in mammalian cells in vitro (Jansson & Hyttinen, 1994; Maki-Paakkanen & Hakulinen, 2008) including human cells (Chang, Daniel, & Deangelo, 1991) such as sister chromatid
exchange (SCE), chromosomal aberrations (Hyttinen et al.