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chromatolysis

   Also found in: Medical 0.04 sec.
chro·ma·tol·y·sis  (krm-tl-ss)
n.
The dissolution or disintegration of chromophil material, such as chromatin, within a cell.
chro·mato·lytic (-mtl-tk) adj.
chromatolysis [ˌkrəʊməˈtɒlɪsɪs]
n
(Life Sciences & Allied Applications / Biology) Cytology the dissolution of stained material, such as chromatin in injured cells
chromatolysis
the breakdown of the protoplasm that contains the genes in the cell nucleus.
See also: Cells


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Beginning on day 5, however, neuronal degeneration was seen in many areas, manifested by shrinkage of the perikaryon with intense eosinophilia of the cytoplasm, central chromatolysis, and condensation of the nucleus.
West Nile Virus Infection in the Golden Hamster (Mesocricetus ... by Tesh, Robert B. / Emerging Infectious Diseases
In the central nervous system, the neural cell body undergoes chromatolysis with peripheral shifting of the Nissl bodies (stocked metabolites) and a decrease in their number.
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This same drug also produced vestibulocochlear Wallerian-like degeneration and retinal ganglion cell chromatolysis in dogs treated for 14 weeks at 180 mg/kg/day, a dose that resulted in a mean plasma drug level similar to that seen with the 60 mg/kg/day dose.
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