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chromosomal |
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| A study in the 21 December 2005 Journal of the National Cancer Institute now shows a genetic difference between melanoma patients and those with other skin cancers: melanoma patients' chromosomal DNA (chromarin) suffers less damage than other skin cancer patients' when cells are irradiated with ultraviolet B (UVB) light, the part of UV that causes sunburn. Under this partnership, the three companies will strive to develop an agent that inhibits the activity of Cdc7-ASK kinase, which plays a role in chromosomal DNA replication. They found identical complex chromosomal anomalies in the cancer cells of all of the 11 afflicted animals studied. |
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