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chromosomal aberration

   Also found in: Medical, Acronyms, Encyclopedia, Wikipedia 0.01 sec.
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Noun1.chromosomal aberration - any change in the normal structure or number of chromosomes; often results in physical or mental abnormalities
aberrance, aberrancy, aberration, deviance - a state or condition markedly different from the norm
monosomy - chromosomal abnormality consisting of the absence of one chromosome from the normal diploid number
trisomy - chrosomal abnormality in which there is one more than the normal number of chromosomes in a cell
sex-linked disorder - any disease or abnormality that is determined by the sex hormones; "hemophilia is determined by a gene defect on an X chromosome"


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BACKGROUND: Many bacterial or mammalian cell-based test systems, such as the Ames test, chromosomal aberration assays, or gene mutation assays, are commonly used in developed countries to detect the genotoxicity of industrial chemicals.
Before Rowley began investigations into the chromosomal abnormalities of leukemia at the University of Chicago in the 1960s, few scientists believed that chromosomal aberrations caused tumors.
Specific topics include its stability during food processing and storage, chromosomal aberrations, cataract and oxidative stress, and prostate and breast cancer.
 
 
 
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