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chromosomal anomaly

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Noun1.chromosomal anomaly - any change in the normal structure or number of chromosomes; often results in physical or mental abnormalities
chromosomal aberration, chromosonal disorder, chrosomal abnormality
aberrance, aberrancy, aberration, deviance - a state or condition markedly different from the norm
monosomy - chromosomal abnormality consisting of the absence of one chromosome from the normal diploid number
trisomy - chrosomal abnormality in which there is one more than the normal number of chromosomes in a cell
sex-linked disorder - any disease or abnormality that is determined by the sex hormones; "hemophilia is determined by a gene defect on an X chromosome"
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Down syndrome, or trisomy 21, is the most commonly occurring chromosomal anomaly in the world.
Enjoying my daughter with Down syndrome: a hip mom employs holistic ... by Martinez, Lizzie / Mothering
Jerome Lejeune, the first president of the Pontifical Academy for Life and the French scientist who identified Downs syndrome as a chromosomal anomaly, is being proposed for beatification.
Jerome Lejeune proposed for beatification by Catholic Insight
Down's syndrome, or trisomy 21, is a chromosomal anomaly leading to lower-than-normal mental ability, increased susceptibility to infections and higher incidence of leukemia, as well as to characteristic slanted eyes and skeletal abnormalities.
A common medical denominator; specific neuropathological changes ... by Edwards, Diane D. / Science News
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