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|Noun||1.||chromosonal disorder - any change in the normal structure or number of chromosomes; often results in physical or mental abnormalities|
monosomy - chromosomal abnormality consisting of the absence of one chromosome from the normal diploid number
trisomy - chrosomal abnormality in which there is one more than the normal number of chromosomes in a cell
sex-linked disorder - any disease or abnormality that is determined by the sex hormones; "hemophilia is determined by a gene defect on an X chromosome"