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Related to ciclosporin: tacrolimus


Variant of cyclosporine.


(ˌsaɪkləʊˈspɔːrɪn) or


(Pharmacology) a drug extracted from a fungus and used after organ transplantation to suppress the body's immune mechanisms, and so prevent rejection of an organ
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is approved for the treatment of moderate to severe plaque psoriasis in adults who failed to respond to, or who have a contraindication to, or are intolerant to other systemic therapies including ciclosporin, MTX or psoralen plus ultraviolet A (PUVA).
Contract awarded for event 4279/15, ciclosporin microemulsion 100mg / ml.
Steroid-sparing immunosuppressive agents such as methotrexate, mycophenolate, azathioprine or ciclosporin can be introduced to reduce or replace steroid treatment.
Twice-daily ciclosporin capsules produced an almost immediate improvement.
Are switches from oral to subcutaneous methotrexate or addition of ciclosporin to methotrexate useful steps in a tight control treatment strategy for rheumatoid arthritis?
The team evaluated results from 33 patients who were treated with prednisolone and chlorambucil, 37 patients with ciclosporin and 38 who were provided with supportive therapy alone.
Whether or not ciclosporin, a known risk factor for development of PTLD, played a part in the initial development of our patient's disease is also open to conjecture.
Edmonds EVJ, Morris SD, Short K, Bewley SJ, Eady RAJ: Pustular psoriasis of pregnancy treated with ciclosporin and high dose prednisolone.
Ciclosporin A tapering monitored by NFAT-regulated gene expression: a new concept of individual immunosuppression.
5 mg/kg per day of ciclosporin or methotrexate plus placebo-ciclosporin.
The introduction of ciclosporin in the mid 1980s was a major advance, leading to 1-year survival rates of more than 90% and graft survival of 80%.