At least two are in phase III, placebo-controlled trials: Axokine, or ciliary
neurotrophic factor (Regeneron Pharmaceuticals), and Rimonabant, a cannabinoid receptor agonist (Sanofi-Sythelabo).
Intraocular medulloepithelioma is a congenital tumor of the nonpigmented ciliary
epithelium, usually diagnosed in childhood.
In the human body, in which organ are the ciliary
muscles situated: the eye or the liver?
It has a new chapter on the Cachet and more information on previous designs that have been updated, including the iris fixated Ophtec Artisan IOL and the foldable posterior changer, ciliary
sulcus fixated styles of the intraocular collamer lens from Staar and the phakic refractive lens.
As a selective inhibitor of ENaC, if it is ultimately approved for marketing, P-1037 could provide a long-acting treatment for a variety of chronic bronchitic lung conditions including cystic fibrosis, COPD, primary ciliary
dyskenesia and non-CF bronchiectasis.
Analysing the morphology of the photoreceptors in the starfish eyes, the researchers further confirmed that they constitute an intermediate state between the two large known groups of rhabdomeric and ciliary
photoreceptors, in that they have both microvilli and a modified cilium.
The second study used longer needles (700-800 [micro]m) to precisely deliver anti-glaucoma drugs between layers near the ciliary
Six muscles around each eye control eye movements, and a ciliary
muscle located behind each iris (the colored eye membrane) controls eye focus.
Darryl su'ers from primary ciliary
dyskinesia (PCD) - a rare genetic disorder which means he has to spend at least eight weeks a year in hospital.
Founded in 2009 on the basis of work conducted by Professor Francine Behar-Cohen (Inserm Unit, U872, Centre de Recherche des Cordeliers, and Chief Medical Director of the Gonin Ophthalmic Hospital in Lausanne), the Company is developing a novel therapeutic approach in ophthalmology based on the electroporation into the ciliary
muscle of plasmids encoding therapeutic proteins.
The paper, entitled: "The dual phosphodiesterase 3 and 4 inhibitor RPL554 stimulates CFTR and ciliary
beating in primary cultures of bronchial epithelia" was published on-line in the peer reviewed Journal "American Journal of Physiology - Lung Cellular and Molecular Physiology" on 6 November 2015.
Four-week-old animals were given doses of a modified virus in one eye in order to make their retinas produce a human protein, called ciliary
neurotrophic factor (CNTF), which may be toxic at high doses.