cisplatin


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cis·plat·in

 (sĭs-plăt′n, -plā′tn)
n.
A platinum-containing chemotherapeutic drug, Cl2H6N2Pt, used in the treatment of metastatic ovarian or testicular cancers and advanced bladder cancer. Also called cisplatinum.

[Short for cisplatinum.]

cisplatin

(sɪsˈplætɪn)
n
(Pharmacology) a cytotoxic drug that acts by preventing DNA replication and hence cell division, used in the treatment of tumours, esp of the ovary and testis
[C20: from cis- + platin(um)]
Translations

cisplatin

n cisplatino
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References in periodicals archive ?
Cisplatin-resistant sublines (SW480) were selected by double subcloning using the limiting dilution method from cultures continuously exposed to increasing concentrations of cisplatin (14).
Eight patients with advanced biliary tract cancer received Acelarin and cisplatin on days one and eight of a three-week cycle.
Using a highly sensitive technique to measure and map cisplatin in mouse and human inner ear tissues, researchers found that forms of cisplatin build up in the inner ear.
The antioxidant effect of p-Coumaric acid was evaluated against brain damage induced by cisplatin in rats.
A single dose of cisplatin 10mg/kg was given as I/P injection to the toxic group.
Concurrent chemo-RT included 60–66 Gray (Gy) of RT with weekly cisplatin and was similar in both the arms.
In mice the addition of 1 [micro]L of fish oil to cisplatin was sufficient to induce chemoresistance, to the degree that treatment no longer inhibited tumor growth.
5] Cisplatin and 5-fluorouracil (FU) with or without other drugs in oral cancer remain to be the most preferred regimen.
Platinum coordination compounds have been successfully applied in cancer chemotherapy for more than 25years since the introduction of the parent compound for this class of antitumor agents, namely, cis-[diamminedichloro-platinum(II)] (1) known as cisplatin (Fig 1a & b).
Chemotherapy is one of the most common treatments (2, 3) and cisplatin (CP) as a member of the platinum drugs is used to treat testicular, ovarian, breast, lung, and bladder cancers (4).