classical pathway


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Related to classical pathway: alternative pathway, Complement system

classical pathway

n. Immunology
The activation of complement by an antigen-antibody complex. This pathway contrasts with the alternative pathway, which does not depend on the presence of antibodies.
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The classical pathway is triggered by antigen-bound antibody molecules and is initiated by the binding of a specific part of the antibody molecule (Fc) to the C1 component.
The 2 morphologic multistep pathways are the classical pathway (the so-called adenoma-carcinoma sequence) and the serrated neoplasia pathway.
Classical pathway of complement is initiated by producing antibodies by natural antibodies, C-reactive protein, or serum amyloid protein [5].
Hemolytic activity in classical pathway and alternative pathway was associated with variation of the porcine genes encoding the complement components pC3 (Wimmers et al.
Then, CRP is able to interact with C1q, activating the classical pathway of the complement system [49].
Classical pathway complement levels divide UV into normocomplementemic (NUV) and hypocomplementem-ic (HUV) forms.
For example, compared with classical pathway optimization, which focuses on enhancing the biosynthetic pathway of the nutraceutical ingredient, metabolic engineering provides a holistic view of the micro-organism, thereby optimizing the whole production organism.
classical pathway (CP), alternative pathway (AP), and lectin pathway (LP).