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clofibrate

   Also found in: Medical, Wikipedia 0.26 sec.
clo·fi·brate  (kl-fbrt, -fbrt)
n.
A synthetic drug, C12H15ClO3, used primarily to reduce abnormally elevated levels of plasma cholesterol and triglyceride.

[clofibr(ic acid) (perhaps c(h)lo(ro)- + fibr(o)- + -ic) + -ate.]
ThesaurusLegend:  Synonyms Related Words Antonyms
Noun1.clofibrate - a drug (trade name Atromid-S) that reduces lipids in the blood serum; used to treat some cardiovascular diseases
medicament, medication, medicinal drug, medicine - (medicine) something that treats or prevents or alleviates the symptoms of disease


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In two clinical trials with patients who had elevated blood lipid levels, the use of gugulipid extract was found to be just as effective as clofibrate (a cholesterol-lowering medication).
Within the ILSI/HESI consortium, the hepatotoxicity working group evaluated the two hepatotoxicants methapyrilene (MP) and clofibrate by gene expression analysis of rat livers (Baker et al.
The Stockholm Ischemic Heart Disease Secondary Prevention Study showed a 28% decrease in both ischemic heart disease and total mortality in a small number of patients greater than 60 years of age when treated with a combination of clofibrate and niacin.
 
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