clotting factor


Also found in: Thesaurus, Medical, Legal, Financial, Encyclopedia, Wikipedia.
Related to clotting factor: hemophilia

clotting factor

n
(Biochemistry) any one of a group of substances, including factor VIII, the presence of which in the blood is essential for blood clotting to occur. Also called: coagulation factor
ThesaurusAntonymsRelated WordsSynonymsLegend:
Noun1.clotting factor - any of the factors in the blood whose actions are essential for blood coagulation
plasma protein - any of the proteins in blood plasma
factor I, fibrinogen - a protein present in blood plasma; converts to fibrin when blood clots
factor II, prothrombin - a protein in blood plasma that is the inactive precursor of thrombin
factor III, thrombokinase, thromboplastin - an enzyme liberated from blood platelets that converts prothrombin into thrombin as blood starts to clot
calcium ion, factor IV - ion of calcium; a factor in the clotting of blood
cothromboplastin, factor VII, proconvertin, stable factor - a coagulation factor formed in the kidney under the influence of vitamin K
antihaemophilic factor, antihaemophilic globulin, antihemophilic factor, antihemophilic globulin, factor VIII, Hemofil - a coagulation factor (trade name Hemofil) whose absence is associated with hemophilia A
Christmas factor, factor IX - coagulation factor whose absence is associated with hemophilia B
factor X, prothrombinase - coagulation factor that is converted to an enzyme that converts prothrombin to thrombin in a reaction that depends on calcium ions and other coagulation factors
factor XI, plasma thromboplastin antecedent - coagulation factor whose deficiency results in a hemorrhagic tendency
factor XII, Hageman factor - coagulation factor whose deficiency results in prolongation of clotting time of venous blood
factor XIII, fibrinase - in the clotting of blood thrombin catalyzes factor XIII into its active form (fibrinase) which causes fibrin to form a stable clot
References in periodicals archive ?
Contract notice: The concentrate of clotting factor ix delivered to the patient~s home / to the hemophilia treatment center; investigation sign: zzp-184/15 pos.
Normally, 20-30% of people who get infusions of clotting factor develop antibodies against them that interfere with treatment.
Hemophilia is a hereditary bleeding disorder caused by a lack of clotting factor VIII or IX, though not rare, which affects mostly males.
The most common type of the condition is haemophilia A, where people lack clotting factor FVIII.
Naeem Leghari said that the primary treatment for moderate to severe hemophilia is factor replacement therapy, which involves replacing the bloods deficient clotting factor.
Their cardiovascular health was assessed by means of lab tests and physical examinations, to check on blood fats, blood sugars, and blood clotting factor, high levels of which are linked to a raised heart attack and stroke risk.
The incidence of bleeding fell by 2% (1--3%) for every 1% increase in clotting factor concentration.
Because the aPTT remained prolonged 2 days after admission (a total of 7 days after the last dabigatran intake), clotting factor activities were quantified.
An experimental gene therapy technique boosted the production of a vital blood clotting factor in six people with hemophilia B, according to new research supported by the National Institutes of Health.
His history of hepatic GVHD might cause clotting factor deficiency.
com), a provider of specialty pharmacy services to clients with chronic illnesses who need clotting factor, IVIg and other medication, has announced that the pharmacy sponsored the Virginia Hemophilia Foundation annual meeting, held May 14-15 at Camp Holiday Trails in Charlottesville, Va.
The severity of a person's bleeding disorder usually depends on the amount of clotting factor that is missing or not working.