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clozapine

   Also found in: Medical, Wikipedia 0.06 sec.
clo·za·pine  (klz-pn, -pn)
n.
An antipsychotic drug used as a sedative and in the treatment of schizophrenia.
[c(h)lo(ro)- + alteration of (dia)zepine (diazep(am) + -ine).]
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Noun1.clozapine - an antipsychotic drug (trade name Clozaril) used as a sedative and for treatment-resistant schizophrenia; know to have few side effects
Clozaril
antipsychotic, antipsychotic agent, antipsychotic drug, major tranquilizer, major tranquilliser, major tranquillizer, neuroleptic, neuroleptic agent, neuroleptic drug - tranquilizer used to treat psychotic conditions when a calming effect is desired
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7), we said that St John's wort may increase the activity of protease inhibitors, digitalis, statins, warfarin, chemotherapy drugs, oral contraceptives, tricyclic antidepressants, and clozapine, olanzapine, and theophylline.
Correction by Nutrition Action Healthletter
In some cases, the newer, atypical antipsychotic drugs such as clozapine or olanzapine may help relieve severe or refractory symptoms of bipolar disorder and prevent recurrences of mania.
Going to Extremes: Bipolar Disorder by Pamphlet by: National Institute of Mental Health
The psychoactive drug clozapine, for example, causes dangerous blood-clotting disorders in about 5% of patients.
Arrays Cast Toxicology in a New Light by Lauerman, John F. / Environmental Health Perspectives
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