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clozapine

   Also found in: Medical, Wikipedia 0.01 sec.
clo·za·pine  (klz-pn, -pn)
n.
An antipsychotic drug used as a sedative and in the treatment of schizophrenia.

[c(h)lo(ro)- + alteration of (dia)zepine (diazep(am) + -ine).]
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Noun1.clozapine - an antipsychotic drug (trade name Clozaril) used as a sedative and for treatment-resistant schizophrenia; know to have few side effects


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Byline: ANI London, July 13 (ANI): Thousands of extra deaths among schizophrenia patients worldwide may have resulted because of the restrictions imposed by authorities on the use of antipsychotic drug clozapine over safety concerns, suggests a new piece of research.
Forty-two patients with chronic, treatment-resistant schizophrenia who were maintained on optimal doses of clozapine were randomly assigned to receive 120 mg per day of Ginkgo biloba extract (ginkgo; standardized to contain 24% flavone glycosides and 6% terpene lactones) or placebo in addition to clozapine for 12 weeks.
However, he experiences drooling to the point of wanting the clozapine discontinued.
 
 
 
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