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 (kŏl′chĭ-sēn′, kŏl′kĭ-)
A poisonous alkaloid, C22H25NO6, that is obtained from the autumn crocus and inhibits microtubule formation. It is used in medicine to treat gout and in plant breeding to produce polyploid plants.


(ˈkɒltʃɪˌsiːn; -sɪn; ˈkɒlkɪ-)
(Biochemistry) a pale-yellow crystalline alkaloid extracted from seeds or corms of the autumn crocus. It is used in the treatment of gout and to create polyploid plants by inhibiting chromosome separation during meiosis. Formula: C22H25NO6
[C19: from colchicum + -ine2]


(ˈkɒl tʃəˌsin, -sɪn, ˈkɒl kə-)

a pale yellow, crystalline alkaloid, C22H25NO6, the active principle of colchicum.
ThesaurusAntonymsRelated WordsSynonymsLegend:
Noun1.colchicine - an analgesic drug derived from the saffron plant and used to treat gout
analgesic, anodyne, pain pill, painkiller - a medicine used to relieve pain


n colchicina
References in periodicals archive ?
Colchicine is particularly effective in the acute attack, but the therapeutic window is very narrow.
2% as the company lowered its guidance for its generics businesses, blaming lower than expected sales growth for its gout drug, Colchicine.
Prognosis of colchicine poisoning is mainly associated with the dose of ingestion and the time of admission after ingestion of the drug.
After initiation of low-dose prednisone and colchicine, the patient's hepatomegaly, functional hyposplenism, albuminuria, and Bence Jones proteinuria resolved.
Results: Stereotaxic ICV infusion of colchicine significantly impaired the RAM performance together with decrease in norepinephrine (NE) level in cerebral cortex (CC), hippocampus (HC) and caudate nucleus (CN).
All of the patients were on indomethacin and colchicine.
A reduction in colchicine dosage or interruption in colchicine is recommended in patients with normal renal or hepatic function.
In the literature; colchicine, steroids, and non-steroidal anti-inflammatory drug treatments have been reported.
Your doctor will confirm gout with blood tests and give you the anti-gout drug colchicine.
However, there was a fatal level of Colchicine in her system - a drug used to treat gout.
Treatment with colchicine, acemetacin, and bisphosphonates was started.
According to a randomized trial published in the New England Journal of Medicine, patients with recurring pericarditis (swelling of the pericardium, the thin membrane surrounding the heart) who are treated with colchicine, a common gout medication, in combination with conventional anti-inflammatory therapy, experienced a significantly reduced rate of incessant or recurrent pericarditis.