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 (kŏl′chĭ-sēn′, kŏl′kĭ-)
A poisonous alkaloid, C22H25NO6, that is obtained from the autumn crocus and inhibits microtubule formation. It is used in medicine to treat gout and in plant breeding to produce polyploid plants.


(ˈkɒltʃɪˌsiːn; -sɪn; ˈkɒlkɪ-)
(Biochemistry) a pale-yellow crystalline alkaloid extracted from seeds or corms of the autumn crocus. It is used in the treatment of gout and to create polyploid plants by inhibiting chromosome separation during meiosis. Formula: C22H25NO6
[C19: from colchicum + -ine2]


(ˈkɒl tʃəˌsin, -sɪn, ˈkɒl kə-)

a pale yellow, crystalline alkaloid, C22H25NO6, the active principle of colchicum.
ThesaurusAntonymsRelated WordsSynonymsLegend:
Noun1.colchicine - an analgesic drug derived from the saffron plant and used to treat gout
analgesic, anodyne, pain pill, painkiller - a medicine used to relieve pain


n colchicina
References in periodicals archive ?
One study found "a reduction in colchicine initiation and an increase in patient spending .
Colchicine treatment was started and a complete response was obtained.
The current study was designed to evaluate the effect of colchicine on cellular immune responses in mice.
To that end, Gensco Pharma--a specialty pharmaceutical company focusing on research, development and marketing of transdermal prescription products--has developed a new transdermal colchicine gel to treat these sudden flare-ups.
Our findings suggest that both naproxen and low-dose colchicine are effective treatments for acute gout," Edward Roddy, MD, said at the British Society for Rheumatology annual conference.
Present research emphasized (i) evaluation of four different inducer lines for in-vivo maternal haploid induction and (ii) effectiveness of chromosome doubling with colchicine and pendimethalin herbicide treatments.
Those patients who cannot take NSAIDs and colchicine or colchicine is ineffective may be treated with corticosteroids.
Another aspect to be considered, and usually neglected, is the delayed effect of colchicine (LUCKETT, 1989), the main polyploidization agent used in grasses, which can lead to chromosomal losses and rearrangements with strong impacts on fertility (LUCKETT, 1989).
Background: Gloriosa superba L (glory lily, Colchicaceae) contains colchicine, and related alkaloids such as 3-O-demethylcolchicine and its glycoside colchicoside.
Your doctor can give you the anti-gout drug colchicine and the preventive drugs, allopurinol or probenecid.
Summary: In our continuing search for more potent anticancer agent, eight novel nitrates couple with C-10 colchicine nitric oxide-releasing derivatives (5a-f and 7a-b) were prepared.