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Related to cold agglutinin: Cold Agglutinin Titer


An antibody or other substance that is capable of causing agglutination, as of red blood cells or bacteria.


(Biology) a substance, such as an antibody or a lectin, that causes agglutination of cells or bacteria
[C19: agglutinate + -in]


(əˈglut n ɪn)

an antibody that causes agglutination.
ThesaurusAntonymsRelated WordsSynonymsLegend:
Noun1.agglutinin - an antibody that causes agglutination of a specific antigen
antibody - any of a large variety of proteins normally present in the body or produced in response to an antigen which it neutralizes, thus producing an immune response
isoagglutinin - an antibody produced by one individual that causes agglutination of red blood cells in other individuals of the same species
References in periodicals archive ?
Bioverativ announced that the first patient has been dosed in the Phase 3 clinical program of its investigational therapy BIVV009 for cold agglutinin disease, or CAgD.
Beyond its two marketed products, Bioverativ's pipeline includes a program in Phase 3 testing for cold agglutinin disease, and early stage research programs and collaborations in hemophilia, and other rare blood disorders, including sickle cell disease and beta thalassemia.
Herein, we report a case of cold agglutinin disease (CAD) caused by recurrent viral infections after splenectomy to treat childhood immune thrombocytopenic purpura (ITP).
7) in which 89 adult patients who were diagnosed as having cold agglutinin disease were evaluated retrospectively, it was reported that more than 90% of the patients had a positive Coombs test with anti-C3.
As part of the acquisition, Bioverativ will obtain worldwide rights to True North's lead candidate, TNT009, a monoclonal antibody in development to treat cold agglutinin disease, a hemolytic condition.
The category of cold hemolysins includes 2 distinct disease entities: cold agglutinin syndrome and paroxysmal cold hemoglobinuria, either of which should demonstrate a DAT positive only with C3 antisera.
Food and Drug Administration (FDA) has granted Orphan Drug Designation for the True North Therapeutics's lead product candidate, TNT009 for the treatment of autoimmune hemolytic anemia, including Cold Agglutinin Disease (CAD), a form of autoimmune hemolytic anemia for which there are limited treatment options available for patients.
The publication is titled ''TNT003, an inhibitor of the serine protease C1s, prevents complement activation induced by cold agglutinin disease patient autoantibodies''.
Q When preheating a specimen with a severe cold agglutinin does not work (i.
h) Cold Agglutinin Disease (CAD) is an autoimmune disease characterised by the presence of high concentrations of circulating antibodies, usually IgM, dirested against red blood cells.
Diagnosis and treatment of cold agglutinin mediated autoimmune hemolytic anemia.
Thrombocytopenia and even pancytopenia may be present, as well as a cold agglutinin disease characterized by an autoimmune hemolytic anemia.